Protein Alignment CtsB1 and cts12

DIOPT Version :9

• Sequence 1: NP_001259536.2
• Gene: CtsB1 / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: XP_021329137.1
• Gene: cts12 / 567046
• ZFINID: ZDB-GENE-050208-336
• Length: 349
• Species: Danio rerio
• Alignment Length: 344
• Identity: 85/344 - (24%)
• Similarity: 133/344 - (38%)
• Gaps: 92/344 - (26%)

  Fly    26 DEFIEVVRSKA-------KTWTVGRNFD-------------ASVTEGHIRRLMGVH--------- 61
            ||..|.|..|.       |.|....:|.             ..:|....:||:|..
Zfish    53 DEESEDVHRKTIWETNMQKIWKNNNDFSFGLSMFKMAMNKYGDLTSVEYKRLLGSKIKGTGNRKG 117

  Fly    62 --PDAHKFALPDKREVLGDLYVNSVDELPEEFDSRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAM 124
              ..|....|..||     |.|.::|...:.:           :.|::|||.|||||:|....|:
Zfish   118 KITSAQMLRLNAKR-----LGVTNIDYRAKGY-----------VTEVKDQGYCGSCWSFSTTGAI 166

  Fly   125 SDRVCIHSGGKVNFHFSADDLVSCCHTCG-FGCNGGFPGAAWSYWTRKGIVSGGPYGSNQGCRPY 188
            ..::..|:|..|:  .|...||.|..:.| :||:|.:...|:.|.....:.|...|       ||
Zfish   167 EGQMYKHTGRLVS--LSEQQLVDCSRSYGTYGCSGAWMANAYDYVINNALESSDTY-------PY 222

  Fly   189 ---EISPCEHHVNGTRPPCAHGGRTPKCSHVCQSGYTVDYAKDKHFGSKSYSVRRNVREIQEEIM 250
               :..||.:..|                 :..:|.: ||         .:....|.:.:.:.:.
Zfish   223 TSVDTQPCFYEKN-----------------LAMAGIS-DY---------RFVPAGNEQALADAVA 260

  Fly   251 TNGPVEGAFTV-YEDLILYKDGVYQHEHGKELG-GHAIRILGWGVWGEEKIPYWLIGNSWNTDWG 313
            |.|||..|... ....:.|..|:|:..:..... .||:.::|:|  .||...||:|.|||.|.||
Zfish   261 TVGPVSVAIDADNPSFLFYSSGIYKESNCNPNNLNHAVLVVGYG--SEEGTDYWIIKNSWGTGWG 323

  Fly   314 DHGFFRILR-GQDHCGIES 331
            :.|:.|::| |::.|||.|
Zfish   324 EGGYMRMIRNGKNTCGIAS 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB1	NP_001259536.2	Propeptide_C1	24..64	CDD:285358	12/68 (18%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	66/251 (26%)
cts12	XP_021329137.1	Inhibitor_I29	41..101	CDD:311939	9/47 (19%)
		Peptidase_C1A	135..347	CDD:239068	67/257 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820