Protein Alignment CtsB1 and AgaP_AGAP011828

DIOPT Version :9

• Sequence 1: NP_001259536.2
• Gene: CtsB1 / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: XP_001689282.1
• Gene: AgaP_AGAP011828 / 5667926
• VectorBaseID: AGAP011828
• Length: 344
• Species: Anopheles gambiae
• Alignment Length: 388
• Identity: 105/388 - (27%)
• Similarity: 154/388 - (39%)
• Gaps: 108/388 - (27%)

  Fly     3 LLLLVATAASVAALTSGEPSLLSDEFIEVVRSKAKTWTV-----GRNFDASVTEGHIRRLMGVHP 62
            |:|::...|:..|::          ..|:|:.:   ||.     .:.:| |.||..||..:.|.
Mosquito     5 LILILGFVAAANAIS----------IFELVKEE---WTAFKLQHRKKYD-SETEERIRMKIYVQ- 54

  Fly    63 DAHKFALPDKREVLGD----LYVNS-VDELPEEF------------------------------- 91
            :.||.|..::|..||.    |.||. .|.|.|||
Mosquito    55 NKHKIAKHNQRYDLGQEKFRLRVNKYADLLHEEFVHTLNGFNRSVSGKGQLLRGELKPIEEPVTW 119

  Fly    92 --------DSRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSADDLVSC 148
                    .:...|.....:.:::|||.|||||:|.|..|:..:....:|..|:  .|..:||.|
Mosquito   120 IEPANVDVPTAMDWRTKGAVTQVKDQGHCGSCWSFSATGALEGQHFRKTGKLVS--LSEQNLVDC 182

  Fly   149 CHTCG-FGCNGGFPGAAWSY-WTRKGIVSGGPYGSNQGCRPYEISPCEHHVNGTRPPCAHGGRTP 211
            ....| .|||||....|:.| ...|||.:...|       |||....|.|.|            |
Mosquito   183 SQKYGNNGCNGGMMDFAFQYIKDNKGIDTEKSY-------PYEAIDDECHYN------------P 228

  Fly   212 KCSHVCQSGYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNGPVEGAFTV-YEDLILYKDGV-YQ 274
            |.......|: ||..:.            |.:.:.:.:.|.|||..|... :|....|.:|| |:
Mosquito   229 KAVGATDKGF-VDIPQG------------NEKALMKALATVGPVSVAIDASHESFQFYSEGVYYE 280

  Fly   275 HEHGKELGGHAIRILGWGVW--GEEKIPYWLIGNSWNTDWGDHGFFRILRGQD-HCGIESSIS 334
            .:...|...|.:..:|:|..  ||:   |||:.|||.|.|||.|:.::.|.:| ||||.::.|
Mosquito   281 PQCDSEQLDHGVLAVGYGTTEDGED---YWLVKNSWGTTWGDQGYVKMARNRDNHCGIATTAS 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB1	NP_001259536.2	Propeptide_C1	24..64	CDD:285358	11/44 (25%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	79/293 (27%)
AgaP_AGAP011828	XP_001689282.1	PTZ00203	6..343	CDD:185513	104/387 (27%)
		Inhibitor_I29	28..87	CDD:214853	20/60 (33%)
		Peptidase_C1	127..343	CDD:278538	76/251 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820