Protein Alignment CtsB1 and Ctsll3

DIOPT Version :9

• Sequence 1: NP_001259536.2
• Gene: CtsB1 / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: XP_006253592.1
• Gene: Ctsll3 / 498691
• RGDID: 1560071
• Length: 330
• Species: Rattus norvegicus
• Alignment Length: 366
• Identity: 92/366 - (25%)
• Similarity: 147/366 - (40%)
• Gaps: 72/366 - (19%)

  Fly     1 MNLLLLVAT--AASVAALTSGEPSLLSDEFIEVVRSK-AKTWTVGRNFDASVTEGHIRRLMGVHP 62
            |..:.|:||  ...::|..:.:||.  |...|..::| .||:.............:..:::.:|.
  Rat     1 MTPIFLLATLCLGMISAAPTHDPSF--DTVWEEWKTKHGKTYNTNEEGQKRAVWENNMKMINLHN 63

  Fly    63 D-----AHKFALPDKREVLGDLYVNSVDELPEEFDSRK-------------------QWPNCPTI 103
            :     .|.|:|  :....|||......||...|..:|                   .|.....:
  Rat    64 EDYLKGKHGFSL--EMNAFGDLTNTEFRELMTGFQGQKTKMMKVFPEPFLGDVPKTVDWRKHGYV 126

  Fly   104 GEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSADDLVSCCHTCG-FGCNGGFPGAAWSY 167
            ..:::||.|||||||.||.::..:|...:|..|  ..|..:||.|..:.| .||:||.|..|:.|
  Rat   127 TPVKNQGPCGSCWAFSAVGSLEGQVFRKTGKLV--PLSEQNLVDCSWSHGNKGCDGGLPDFAFQY 189

  Fly   168 -WTRKGIVSGGPYGSNQGCRPYEISPCEHHVNGTRPPCAHGGRTPKCSHVCQSGYTVDYAKDKHF 231
             ....|:.:...|       |||.      :|||                |:  |...|:..|..
  Rat   190 VKDNGGLDTSVSY-------PYEA------LNGT----------------CR--YNPKYSAAKVV 223

  Fly   232 GSKSYSVRRNVREIQEEIMTNGPVE-GAFTVYEDLILYKDGVYQHEHGKELG-GHAIRILGWGVW 294
            |..|.....|.  :.:.:.|.||:. |....::....||.|:|......... .||:.::|:|..
  Rat   224 GFMSIPPSENA--LMKAVATVGPISVGIDIKHKSFQFYKGGMYYEPDCSSTNLNHAVLVVGYGEE 286

  Fly   295 GEEKIPYWLIGNSWNTDWGDHGFFRILRG-QDHCGIESSIS 334
            .:.: .|||:.|||..|||..|:.::.:. .::|||.|..|
  Rat   287 SDGR-KYWLVKNSWGRDWGMDGYIKMAKDWNNNCGIASDAS 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB1	NP_001259536.2	Propeptide_C1	24..64	CDD:285358	6/45 (13%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	71/271 (26%)
Ctsll3	XP_006253592.1	Inhibitor_I29	29..87	CDD:214853	11/59 (19%)
		Peptidase_C1	114..329	CDD:278538	69/249 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820