Protein Alignment CtsB and Ctsrl1

DIOPT Version :10

• Sequence 1: NP_572920.1
• Gene: CtsB / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001017509.1
• Gene: Ctsrl1 / 498688
• RGDID: 1562210
• Length: 334
• Species: Rattus norvegicus
• Alignment Length: 328
• Identity: 86/328 - (26%)
• Similarity: 125/328 - (38%)
• Gaps: 73/328 - (22%)

  Fly    16 LTSGEPSLLSDEFIEVVRSKAKTWTVGRNFDASVTEGHIRRLMGVHP-DAHKFALPDKREVLGDL 79
            |.:||..|..:.|           |:..|.....|....|::|...| ..|:......:...|.:
  Rat    61 LHNGENGLGKNGF-----------TMEINEFGDTTGEEFRKMMVEFPVQTHREGKSIMKRAAGSI 114

  Fly    80 YVNSVDELPEEFDSRKQWPNCPTIGEIRDQGSCGSCWAF---GAVEAMSDRVCIHSGGKVNFHFS 141
            :...||           |.....:..:|.||:|.:||||   ||:||.:    |...||: ...|
  Rat   115 FPKFVD-----------WRKKGYVTPVRRQGNCNACWAFSVTGAIEAQT----IWQSGKL-IPLS 163

  Fly   142 ADDLVSCCHTCG-FGCNGGFPGAAWSYWTRK-GIVSGGPYGSNQGCRPYEISPCEHHVNGTRPPC 204
            ..:||.|....| .||.||....|:.|.... |:.|...|       |||         |...||
  Rat   164 VQNLVDCSKPQGNNGCLGGDTYNAFQYVLHNGGLQSEATY-------PYE---------GKDGPC 212

  Fly   205 AHGGRTPKCSHVCQSGYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNGPVE-GAFTVYEDLILY 268
            .:   .||.|....:|:.              |:..:...:...:.|.||:. |....:|....|
  Rat   213 RY---NPKNSSAEITGFV--------------SLPESEDILMVAVATIGPISAGIDASHESFKFY 260

  Fly   269 KDGVYQHEHGKELGG--HAIRILGWGVWGEEK--IPYWLIGNSWNTDWGDHGFFRILRGQ-DHCG 328
            |.|:| ||.......  |.:.::|:|..|.:.  ..||||.|||...||..|:.:|.:.: :||.
  Rat   261 KKGIY-HEPNCSSNSVTHGVLVVGYGFKGNDTGGDHYWLIKNSWGKQWGIRGYMKITKDKNNHCA 324

  Fly   329 IES 331
            |.|
  Rat   325 IAS 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB	NP_572920.1	Propeptide_C1	24..64	CDD:462365	7/40 (18%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	71/255 (28%)
Ctsrl1	NP_001017509.1	Inhibitor_I29	29..87	CDD:214853	8/36 (22%)
		Peptidase_C1A	116..332	CDD:239068	73/262 (28%)