Protein Alignment CtsB1 and MGC114246

DIOPT Version :9

• Sequence 1: NP_001259536.2
• Gene: CtsB1 / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001017509.1
• Gene: MGC114246 / 498688
• RGDID: 1562210
• Length: 334
• Species: Rattus norvegicus
• Alignment Length: 328
• Identity: 86/328 - (26%)
• Similarity: 125/328 - (38%)
• Gaps: 73/328 - (22%)

  Fly    16 LTSGEPSLLSDEFIEVVRSKAKTWTVGRNFDASVTEGHIRRLMGVHP-DAHKFALPDKREVLGDL 79
            |.:||..|..:.|           |:..|.....|....|::|...| ..|:......:...|.:
  Rat    61 LHNGENGLGKNGF-----------TMEINEFGDTTGEEFRKMMVEFPVQTHREGKSIMKRAAGSI 114

  Fly    80 YVNSVDELPEEFDSRKQWPNCPTIGEIRDQGSCGSCWAF---GAVEAMSDRVCIHSGGKVNFHFS 141
            :...||           |.....:..:|.||:|.:||||   ||:||.:    |...||: ...|
  Rat   115 FPKFVD-----------WRKKGYVTPVRRQGNCNACWAFSVTGAIEAQT----IWQSGKL-IPLS 163

  Fly   142 ADDLVSCCHTCG-FGCNGGFPGAAWSYWTRK-GIVSGGPYGSNQGCRPYEISPCEHHVNGTRPPC 204
            ..:||.|....| .||.||....|:.|.... |:.|...|       |||         |...||
  Rat   164 VQNLVDCSKPQGNNGCLGGDTYNAFQYVLHNGGLQSEATY-------PYE---------GKDGPC 212

  Fly   205 AHGGRTPKCSHVCQSGYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNGPVE-GAFTVYEDLILY 268
            .:   .||.|....:|:.              |:..:...:...:.|.||:. |....:|....|
  Rat   213 RY---NPKNSSAEITGFV--------------SLPESEDILMVAVATIGPISAGIDASHESFKFY 260

  Fly   269 KDGVYQHEHGKELGG--HAIRILGWGVWGEEK--IPYWLIGNSWNTDWGDHGFFRILRGQ-DHCG 328
            |.|:| ||.......  |.:.::|:|..|.:.  ..||||.|||...||..|:.:|.:.: :||.
  Rat   261 KKGIY-HEPNCSSNSVTHGVLVVGYGFKGNDTGGDHYWLIKNSWGKQWGIRGYMKITKDKNNHCA 324

  Fly   329 IES 331
            |.|
  Rat   325 IAS 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB1	NP_001259536.2	Propeptide_C1	24..64	CDD:285358	7/40 (18%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	71/255 (28%)
MGC114246	NP_001017509.1	PTZ00203	7..332	CDD:185513	86/328 (26%)
		Inhibitor_I29	29..87	CDD:214853	8/36 (22%)
		Peptidase_C1A	116..332	CDD:239068	73/262 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820