Protein Alignment CtsB and ctsl.1

DIOPT Version :10

• Sequence 1: NP_572920.1
• Gene: CtsB / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001002368.1
• Gene: ctsl.1 / 436641
• ZFINID: ZDB-GENE-040718-61
• Length: 334
• Species: Danio rerio
• Alignment Length: 378
• Identity: 102/378 - (26%)
• Similarity: 148/378 - (39%)
• Gaps: 98/378 - (25%)

  Fly     5 LLVATAASVAALTSGEPSLLSDEFIEVVRSKAKTWTV--GRNFDASVTEGH-------IRRLMGV 60
            :||..||.:|..::...||...||        ..|.:  |:::.::..|.|       .|:|:.|
Zfish     3 VLVVAAAFLAVASAASLSLEDMEF--------HAWKLKFGKSYRSAEEESHRQLTWLTNRKLVLV 59

  Fly    61 HPDAHKFALPDKREVLGDLYVNSVDELPEE------------------------FDSRK------ 95
            |.......|...|  ||..|.  .|...||                        |..||
Zfish    60 HNMMADQGLKSYR--LGMTYF--ADMSNEEYRQLVFRGCLGSMNNTKARGGSTFFRLRKAAVVPD 120

  Fly    96 --QWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSADDLVSCCHTCG-FGCN 157
              .|.:...:.:|:||..|||||||.|..::..:....:|..|:  .|...||.|..:.| :||:
Zfish   121 TVDWRDKGYVTDIKDQKQCGSCWAFSATGSLEGQTFRKTGKLVS--LSEQQLVDCSGSYGNYGCD 183

  Fly   158 GGFPGAAWSY-WTRKGIVSGGPYGSNQGCRPYEISPCEHHVNGTRPPCAHGGRTPKCSHVCQSGY 221
            ||....|:.| ...||:.:...|       |||....|...|    |...|.   .|     :||
Zfish   184 GGLMDQAFQYIEANKGLDTEDSY-------PYEAQDGECRFN----PSTVGA---SC-----TGY 229

  Fly   222 TVDYAKDKHFGSKSYSVRRNVREIQEEIMTNGPVEGAFTV-YEDLILYKDGVYQHE--HGKELGG 283
             ||.|.    |.:|        .:||.:.|.||:..|... :....||..|||...  ...|| .
Zfish   230 -VDIAS----GDES--------ALQEAVATIGPISVAIDAGHSSFQLYSSGVYNEPDCSSSEL-D 280

  Fly   284 HAIRILGWGVW-GEEKIPYWLIGNSWNTDWGDHGFFRILRGQ-DHCGIESSIS 334
            |.:..:|:|.. |::   ||::.|||..|||..|:..:.|.: :.|||.::.|
Zfish   281 HGVLAVGYGSSNGDD---YWIVKNSWGLDWGVQGYILMSRNKSNQCGIATAAS 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB	NP_572920.1	Propeptide_C1	24..64	CDD:462365	10/48 (21%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	79/286 (28%)
ctsl.1	NP_001002368.1	Inhibitor_I29	26..86	CDD:462410	16/71 (23%)
		Peptidase_C1	118..333	CDD:425470	74/251 (29%)