Protein Alignment CtsB and ctsc

DIOPT Version :10

• Sequence 1: NP_572920.1
• Gene: CtsB / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_999887.1
• Gene: ctsc / 368704
• ZFINID: ZDB-GENE-030619-9
• Length: 455
• Species: Danio rerio
• Alignment Length: 337
• Identity: 99/337 - (29%)
• Similarity: 141/337 - (41%)
• Gaps: 72/337 - (21%)

  Fly    28 FIEVVRSKAKTWTVGRNFDASVTEGHIRRLMGVHPDAHKFALPDKR--------EVLGDLYVNSV 84
            |::.:.|..|:||        .|.......:.:|....:...|..|        .|..|  ..:.
Zfish   167 FVDEINSVQKSWT--------ATAYSFHETLSIHEMLRRSGGPASRIPRRVRPVTVAAD--SKAA 221

  Fly    85 DELPEEFDSRKQWPN---CPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSADDLV 146
            ..||:.:|    |.|   ...:..:|:|..||||::|..:..:..||.|.:.......||...:|
Zfish   222 SGLPQHWD----WRNVNGVNFVSPVRNQAQCGSCYSFATMGMLEARVRIQTNNTQQPVFSPQQVV 282

  Fly   147 SCCHTCGFGCNGGFPGAAWSYWTRKGIVSGGPYGSNQGCRPYEISPCEHHVNGTRPPCAHGGRTP 211
            ||.. ...||:||||.....|....|||       .:.|.||         .|:..||   ....
Zfish   283 SCSQ-YSQGCDGGFPYLIGKYIQDFGIV-------EEDCFPY---------TGSDSPC---NLPA 327

  Fly   212 KCSHVCQSGYTVDYAKDKH-----FGSKSYSVRRNVREIQEEIMTNGPVEGAFTVYEDLILYKDG 271
            ||        |..||.|.|     :|..|.|.      :..|::.|||:..|..||.|.:.||:|
Zfish   328 KC--------TKYYASDYHYVGGFYGGCSESA------MMLELVKNGPMGVALEVYPDFMNYKEG 378

  Fly   272 VYQH------EHGKELGGHAIRILGWGVWGEEKIPYWLIGNSWNTDWGDHGFFRILRGQDHCGIE 330
            :|.|      .:..||..||:.::|:|...:....||::.|||.:.||::|||||.||.|.|.||
Zfish   379 IYHHTGLRDANNPFELTNHAVLLVGYGQCHKTGEKYWIVKNSWGSGWGENGFFRIRRGTDECAIE 443

  Fly   331 SSISAG--LPKL 340
            |...|.  :|||
Zfish   444 SIAVAATPIPKL 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB	NP_572920.1	Propeptide_C1	24..64	CDD:462365	7/35 (20%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	83/261 (32%)
ctsc	NP_999887.1	CathepsinC_exc	19..132	CDD:462598
		Peptidase_C1A_CathepsinC	224..452	CDD:239112	85/265 (32%)