DRSC/TRiP Functional Genomics Resources

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Protein Alignment CtsB1 and CG6347

DIOPT Version :9

Sequence 1:NP_001259536.2 Gene:CtsB1 / 32341 FlyBaseID:FBgn0030521 Length:340 Species:Drosophila melanogaster
Sequence 2:NP_610906.1 Gene:CG6347 / 36531 FlyBaseID:FBgn0033874 Length:352 Species:Drosophila melanogaster


Alignment Length:316 Identity:87/316 - (27%)
Similarity:127/316 - (40%) Gaps:73/316 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    41 VGRNFDASVTEGHIRRLMGVHPDAHKFALPDKREVLGDLYVN-----------SVDELPEEFDSR 94
            :|.|..|.:|...|..|:|           .|....|:.|.|           :...|||.||.|
  Fly    84 LGVNTLADMTRKEI
ATLLG-----------SKISEFGERYTNGHINFVTARNPASANLPEMFDWR 137

  Fly    95 KQWPNCPTIGEIRDQG----SCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSADDLVSCCHTCG-F 154
            ::       |.:...|    .||:||:|....|:...:...:|  |....|..:||.|....| .
  Fly   138 EK-------GGVTPPGFQGVGCGACWSFATTGALEGHLFRRTG--VLASLSQQNLVDCADDYGNM 193

  Fly   155 GCNGGFPGAAWSYWTRKGIVSGGPYGSNQGCRPYEISPCEHHVNGTRPPCAHGGRTPKCSHVCQS 219
            ||:|||....:.|....|:.....|       ||..:..:...|.|      .||.|:.|.|...
  Fly   194 GCDGGFQEYGFEYIRDHGVTLANKY-------PYTQTEMQCRQNET------AGRPPRESLVKIR 245

  Fly   220 GYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNGPVEGAFTVYEDLI---LYKDGVYQHE--HGK 279
            .|......|:             .:::|.|.|.||:  |.::..|.|   .|..|:|:.|  :..
  Fly   246 DYATITPGDE-------------EKMKEVIATLGPL--ACSMNADTISFEQYSGGIYEDEECNQG 295

  Fly   280 ELGGHAIRILGWGVWGEEKIPYWLIGNSWNTDWGDHGFFRILRGQ-DHCGIESSIS 334
            || .|::.::|:|.  |....||:|.||::.:||:.||.||||.. ..|||.|..|
  Fly   296 EL-NHSVTVVGYGT--ENGRDYWIIKNSYSQNWGEGGFMRILRNAGGFCGIASECS 348

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CtsB1NP_001259536.2 Propeptide_C1 24..64 CDD:285358 7/22 (32%)
Peptidase_C1A_CathepsinB 88..336 CDD:239111 75/258 (29%)
CG6347NP_610906.1 Inhibitor_I29 38..97 CDD:285458 4/12 (33%)
Peptidase_C1A 131..350 CDD:239068 75/258 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45452953
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG4870
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.740

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