Protein Alignment CtsB1 and Ctsf

DIOPT Version :9

• Sequence 1: NP_001259536.2
• Gene: CtsB1 / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001029282.1
• Gene: Ctsf / 361704
• RGDID: 1308181
• Length: 462
• Species: Rattus norvegicus
• Alignment Length: 269
• Identity: 67/269 - (24%)
• Similarity: 110/269 - (40%)
• Gaps: 66/269 - (24%)

  Fly    83 SVDEL-PEEFDSRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSADDLV 146
            |:::| |.|:|.||:    ..:.|::|||.|||||||.....:..:..::.|..::  .|..:|:
  Rat   244 SINDLAPPEWDWRKK----GAVTEVKDQGMCGSCWAFSVTGNVEGQWFLNRGTLLS--LSEQELL 302

  Fly   147 SCCHTCGFGCNGGFPGAAWSYWTRK---GIVSGGPYGSNQGCRPYEISPCEHHVNGTRPPCAHGG 208
            . |......|.||.|..|  |...|   |:.:...||                         :.|
  Rat   303 D-CDKMDKACMGGLPSNA--YTAIKNLGGLETEDDYG-------------------------YQG 339

  Fly   209 RTPKCSHVCQSGYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNGPVEGAFTVYEDLILYKDGVY 273
            ....|:...|..        |.:.:.|..:.|:..:|...:...||:..|...:        |:.
  Rat   340 HVQACNFSTQMA--------KVYINDSVELSRDENKIAAWLAQKGPISVAINAF--------GMQ 388

  Fly   274 QHEHG-----KELGG-----HAIRILGWGVWGEEKIPYWLIGNSWNTDWGDHGFFRILRGQDHCG 328
            .:.||     :.|..     ||:.::|:|  ....||||.|.|||..|||:.|::.:.||...||
  Rat   389 FYRHGIAHPFRPLCSPWFIDHAVLLVGYG--NRSNIPYWAIKNSWGRDWGEEGYYYLYRGSGACG 451

  Fly   329 IESSISAGL 337
            :.:..|:.:
  Rat   452 VNTMASSAV 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB1	NP_001259536.2	Propeptide_C1	24..64	CDD:285358
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	65/260 (25%)
Ctsf	NP_001029282.1	Inhibitor_I29	165..221	CDD:214853
		Peptidase_C1	249..460	CDD:395062	65/262 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343568
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840