Protein Alignment CtsB1 and ctss2.2

DIOPT Version :9

• Sequence 1: NP_001259536.2
• Gene: CtsB1 / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: XP_009290599.1
• Gene: ctss2.2 / 337572
• ZFINID: ZDB-GENE-050626-55
• Length: 337
• Species: Danio rerio
• Alignment Length: 377
• Identity: 92/377 - (24%)
• Similarity: 153/377 - (40%)
• Gaps: 105/377 - (27%)

  Fly     2 NLLLLVATAASVAALTSGEPSLLSDEFIEVVRSK-AKTWT-----VGR--------------NFD 46
            :||..|..:|::|...:.     .|:..|:.:.| .|.::     |||              |.:
Zfish    12 SLLFAVCCSAALAHFNTN-----LDQHWELWKKKHVKLYSCEDEEVGRRELWERNLELIAIHNLE 71

  Fly    47 ASVTEGHIRRLMGVHPDAHKFAL-----PDKREVLGDLYVNSVDE----------------LPEE 90
            ||         ||:|  ::..|:     ....|:|..|.|..|..                :|:.
Zfish    72 AS---------MGMH--SYDLAINHMADMTTEEILQTLAVTRVPPGFKRPTAEYVSSSFAVVPDT 125

  Fly    91 FDSRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSADDLVSCCHTCG-F 154
            .|    |.:...:..:::||:|||||||.:|.|:..::...:|..|:  .|..:||.|....| .
Zfish   126 LD----WRDKGYVTSVKNQGACGSCWAFSSVGALEGQLMKTTGKLVD--LSPQNLVDCSSKYGNL 184

  Fly   155 GCNGGFPGAAWSYWTRKGIVSGGPYGSNQGCRPYEISPCEHHVNGTRPPCAH--GGRTPKCSHVC 217
            |||||:...|:.|     ::..|...| :...||:         ||:..|.:  ..|...|:
Zfish   185 GCNGGYMSQAFQY-----VIDNGGIDS-ESSYPYQ---------GTQGSCRYDPSQRAANCT--- 231

  Fly   218 QSGYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNGPVEGAF-TVYEDLILYKDGVYQHEHGKEL 281
                           |..:..:.:.:.::|.:...|||..|. ......|.|:.|||......:.
Zfish   232 ---------------SYKFVSQGDEQALKEALANIGPVSVAIDATRPQFIFYRSGVYDDPSCTQK 281

  Fly   282 GGHAIRILGWG-VWGEEKIPYWLIGNSWNTDWGDHGFFRILRGQDH-CGIES 331
            ..|.:..:|:| :.|::   |||:.|||...:||.|:.||.|.::: |||.|
Zfish   282 VNHGVLAVGYGTLSGQD---YWLVKNSWGAGFGDGGYIRIARNKNNMCGIAS 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB1	NP_001259536.2	Propeptide_C1	24..64	CDD:285358	13/59 (22%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	68/250 (27%)
ctss2.2	XP_009290599.1	Inhibitor_I29	34..93	CDD:214853	13/69 (19%)
		Peptidase_C1	122..336	CDD:278538	68/251 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820