Protein Alignment CtsB1 and Ctsw

DIOPT Version :9

• Sequence 1: NP_001259536.2
• Gene: CtsB1 / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001019413.1
• Gene: Ctsw / 293676
• RGDID: 1309354
• Length: 371
• Species: Rattus norvegicus
• Alignment Length: 406
• Identity: 97/406 - (23%)
• Similarity: 144/406 - (35%)
• Gaps: 149/406 - (36%)

  Fly     4 LLLVATAASVAALTSG---EPSLLSDEFIEVVRSKAKTWTVGRNFDASVTEGHIRRLMGVHPDAH 65
            |||.....|.:.||..   .|..|.:.|        |.:.:..|...|....:.||| |:.  ||
  Rat    13 LLLAGQGLSDSLLTKDAGPRPLELKEVF--------KLFQIQFNRSYSNPAEYTRRL-GIF--AH 66

  Fly    66 KFALPDK--------------------REVLGDLY---------VNSVDELPEEFDSRKQW---- 97
            ..|...:                    .|..|.||         :|...::..|     :|
  Rat    67 NLAQAQRLQEEDLGTAEFGQTPFSDLTEEEFGQLYGHQRAPERILNMAKKVKSE-----RWGESV 126

  Fly    98 -PNCP------TIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSADDLVSCCHTCGFG 155
             |.|.      .|..|::||:|..|||..|.:.:.....|.:...|:  .|..:|:. |..||.|
  Rat   127 PPTCDWRKVKNIISSIKNQGNCRCCWAIAAADNIQTLWRIKTQQFVD--VSVQELLD-CDRCGNG 188

  Fly   156 CNGGFPGAAW-SYWT---RKGIVSGGPYGSNQGCRPYEISPCEHHVNGTRPPCAHGGRTPKCSHV 216
            |||||   .| :|.|   ..|:.|...|       |::                 |.:.|   |.
  Rat   189 CNGGF---VWDAYITVLNNSGLASEEDY-------PFQ-----------------GHQKP---HR 223

  Fly   217 CQSGYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNG---------PVEGAFTVYEDLIL---YK 269
            |.:        ||:         |.|..||:..|.:.         .:.|..||..::.|   |:
  Rat   224 CLA--------DKY---------RKVAWIQDFTMLSSNEQVIAGYLAIHGPITVTINMKLLQYYQ 271

  Fly   270 DGVYQHEHG---KELGGHAIRILGWGVWGEEK------------------IPYWLIGNSWNTDWG 313
            .||.:....   ..|..|::.::|   :|:||                  .|||::.|||..:||
  Rat   272 KGVIKATPSTCDPHLVNHSVLLVG---FGKEKGGMQTGTLLSHSRKPRRSTPYWILKNSWGAEWG 333

  Fly   314 DHGFFRILRGQDHCGI 329
            :.|:||:.||.:.|||
  Rat   334 EKGYFRLYRGNNTCGI 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB1	NP_001259536.2	Propeptide_C1	24..64	CDD:285358	9/39 (23%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	73/290 (25%)
Ctsw	NP_001019413.1	Inhibitor_I29	40..96	CDD:214853	11/66 (17%)
		Peptidase_C1	126..356	CDD:278538	71/277 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343567
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740