Protein Alignment CtsB1 and RGD1308751

DIOPT Version :9

• Sequence 1: NP_001259536.2
• Gene: CtsB1 / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: XP_225137.5
• Gene: RGD1308751 / 290981
• RGDID: 1308751
• Length: 330
• Species: Rattus norvegicus
• Alignment Length: 367
• Identity: 89/367 - (24%)
• Similarity: 148/367 - (40%)
• Gaps: 84/367 - (22%)

  Fly     1 MNLLLLVAT--AASVAALTSGEPSLLSDEFIEVVRSK-AKTWTVGRNFDASVTEGHIRRLMGVHP 62
            |..:.|:||  ...::|..:.:||.  |...|..::| .||:.............:..:::.:|.
  Rat     1 MTPIFLLATLCLGMISAAPTHDPSF--DTVWEEWKTKHGKTYNTNEEGQKRAVWENNMKMINLHN 63

  Fly    63 D-----AHKFALPDKREVLGDLYVNSVDELPEEFDS-------------------RKQWPNCPTI 103
            :     .|.|:|  :....|||......||...|.|                   ...|.....:
  Rat    64 EDYLKGKHGFSL--EMNAFGDLTNTEFRELMTGFQSMGPKETTIFREPFLGDIPKSLDWREHGYV 126

  Fly   104 GEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSADDLVSCCHTCG-FGCNGGFPGAAWSY 167
            ..:::||.|||||||.||.::..::...:|..|:  .|..:||.|..:.| .|||||....|:.|
  Rat   127 TPVKNQGQCGSCWAFSAVGSLEGQIFKKTGKLVS--LSEQNLVDCSWSYGNLGCNGGLMEFAFQY 189

  Fly   168 -WTRKGIVSGGPYGSNQGCRPYEISP--CEHHVNGTRPPCAHGGRTPKCSHVCQSGYT-VDYAKD 228
             ...:|:.:|..|.       ||...  |.::              ||.|....:|:. |..::|
  Rat   190 VKENRGLDTGESYA-------YEAQDGLCRYN--------------PKYSAANVTGFVKVPLSED 233

  Fly   229 KHFGSKSYSVRRNVREIQEEIMTNGPVE-GAFTVYEDLILYKDGVYQHE--HGKELGGHAIRILG 290
                           ::...:.:.|||. |..:.::....|..|:|...  ...|: .||:.::|
  Rat   234 ---------------DLMSAVASVGPVSVGIDSHHQSFRFYSGGMYYEPDCSSTEM-DHAVLVVG 282

  Fly   291 WGVWGEEKI--PYWLIGNSWNTDWGDHGFFRILRGQ-DHCGI 329
               :|||..  .|||:.|||..|||..|:.::.:.| ::|||
  Rat   283 ---YGEESDGGKYWLVKNSWGEDWGMDGYIKMAKDQNNNCGI 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB1	NP_001259536.2	Propeptide_C1	24..64	CDD:285358	6/45 (13%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	68/272 (25%)
RGD1308751	XP_225137.5	Inhibitor_I29	29..87	CDD:214853	11/59 (19%)
		Peptidase_C1	114..329	CDD:278538	66/250 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820