Protein Alignment CtsB1 and Cts7

DIOPT Version :9

• Sequence 1: NP_001259536.2
• Gene: CtsB1 / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001099569.1
• Gene: Cts7 / 290970
• RGDID: 1309226
• Length: 331
• Species: Rattus norvegicus
• Alignment Length: 381
• Identity: 89/381 - (23%)
• Similarity: 148/381 - (38%)
• Gaps: 107/381 - (28%)

  Fly     1 MNLLLLVATAASVAALTSGEPSL-LSDEFIEVVRSKAKTWTVG---------------------- 42
            |.:.:.:|.....|||.:..|.. |..|:.|..|:.|||::..
  Rat     1 MTVAVFLAILCLRAALAAPRPDYSLDAEWEEWKRNNAKTYSPEEEKQRRAVWEENVKMIKWHTMQ 65

  Fly    43 -----RNFDASVTE-----GHIRRLMGVHPDAHKFALPD-----KREVLGDLYVNSVDELPEEFD 92
                 .||...:.|     |...|:|   .|:....|.:     ||.|          ::|:..|
  Rat    66 NGLWMNNFTIEMNEFGDMTGEEMRMM---TDSSALTLRNGKHIQKRNV----------KIPKTLD 117

  Fly    93 SRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSADDLVSCCHTCGFG-C 156
                |.:...:..:|.||.||:||||....::..::...:|..:  ..|..:|:.|..|.|.. |
  Rat   118 ----WRDTGCVAPVRSQGGCGACWAFSVAASIESQLFKKTGKLI--PLSVQNLIDCTVTYGNNDC 176

  Fly   157 NGGFPGAAWSYWTRKGIVSGGPYGSNQGCRPYE--ISPCEHHVNGTRPPCAHGGRTPKCSHVCQS 219
            :||.|..|:.|....|.:..      :...|||  :..|.:.              |:.|.|
  Rat   177 SGGKPYTAFQYVKNNGGLEA------EATYPYEAKLRHCRYR--------------PERSVV--- 218

  Fly   220 GYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNGP----VEGAFTVYEDLILYKDGVYQHEH--G 278
                   |...|    :.|.||...:.:.::|.||    ::|:...::   .|:.|:| ||.  .
  Rat   219 -------KIARF----FVVPRNEEALMQALVTYGPIAVAIDGSHASFK---RYRGGIY-HEPKCR 268

  Fly   279 KELGGHAIRILGWGVWG--EEKIPYWLIGNSWNTDWGDHGFFRILRGQ-DHCGIES 331
            ::...|.:.::|:|..|  .|...|||:.||....||:.|:.::.|.| ::|||.|
  Rat   269 RDTLDHGLLLVGYGYEGHESENRKYWLLKNSHGEQWGERGYMKLPRDQNNYCGIAS 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB1	NP_001259536.2	Propeptide_C1	24..64	CDD:285358	13/71 (18%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	65/256 (25%)
Cts7	NP_001099569.1	PTZ00203	3..325	CDD:185513	88/379 (23%)
		Inhibitor_I29	29..87	CDD:214853	9/57 (16%)
		Nuclear localization signal. /evidence=ECO:0000250|UniProtKB:Q91ZF2	33..50		4/16 (25%)
		Peptidase_C1A	113..329	CDD:239068	65/256 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820