Protein Alignment CtsB1 and Ctsh

DIOPT Version :9

• Sequence 1: NP_001259536.2
• Gene: CtsB1 / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_037071.1
• Gene: Ctsh / 25425
• RGDID: 2447
• Length: 333
• Species: Rattus norvegicus
• Alignment Length: 328
• Identity: 83/328 - (25%)
• Similarity: 135/328 - (41%)
• Gaps: 73/328 - (22%)

  Fly    29 IEVVRSKAKTWTVGRNFDASVTEGHIRRLMGVHPDAHKF--ALPDKREVLGDLYVNSVDELPEEF 91
            |:....:..|:.:|.|..:.::...|:         ||:  :.|.........|:......|...
  Rat    63 IQAHNQRNHTFKMGLNQFSDMSFAEIK---------HKYLWSEPQNCSATKSNYLRGTGPYPSSM 118

  Fly    92 DSRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSADDLVSCCHTC-GFG 155
            |.||:.   ..:..:::||:|||||.|....|:...|.|.||..:.  .:...||.|.... ..|
  Rat   119 DWRKKG---NVVSPVKNQGACGSCWTFSTTGALESAVAIASGKMMT--LAEQQLVDCAQNFNNHG 178

  Fly   156 CNGGFPGAAWSY-WTRKGIVSGGPYGSNQGCRPYEISPCEHHVNGTRPPCAHGGRTPKCSHVCQS 219
            |.||.|..|:.| ...|||:....|       ||.                  |:..:|
  Rat   179 CQGGLPSQAFEYILYNKGIMGEDSY-------PYI------------------GKNGQC------ 212

  Fly   220 GYTVDYAKDKHFGSKSYSVRRNVREIQ--------EEIMTNGPVEGAFTVYEDLILYKDGVYQ-- 274
                     |....|:.:..:||..|.        |.:....||..||.|.||.::||.|||.
  Rat   213 ---------KFNPEKAVAFVKNVVNITLNDEAAMVEAVALYNPVSFAFEVTEDFMMYKSGVYSSN 268

  Fly   275 --HEHGKELGGHAIRILGWGVWGEEKIPYWLIGNSWNTDWGDHGFFRILRGQDHCGIESSISAGL 337
              |:...:: .||:..:|:|  .:..:.||::.|||.::||::|:|.|.||::.||:.:..|..:
  Rat   269 SCHKTPDKV-NHAVLAVGYG--EQNGLLYWIVKNSWGSNWGNNGYFLIERGKNMCGLAACASYPI 330

  Fly   338 PKL 340
            |::
  Rat   331 PQV 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB1	NP_001259536.2	Propeptide_C1	24..64	CDD:285358	5/34 (15%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	73/261 (28%)
Ctsh	NP_037071.1	Inhibitor_I29	33..88	CDD:400519	4/24 (17%)
		Peptidase_C1	115..330	CDD:395062	73/262 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820