DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CtsB1 and C32B5.13

DIOPT Version :9

Sequence 1:	NP_001259536.2	Gene:	CtsB1 / 32341	FlyBaseID:	FBgn0030521	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_493866.1	Gene:	C32B5.13 / 183116	WormBaseID:	WBGene00016306	Length:	150	Species:	Caenorhabditis elegans

Alignment Length:	136	Identity:	33/136 - (24%)
Similarity:	54/136 - (39%)	Gaps:	27/136 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   191 SPCEHHV--------NGTRPPCAH---GGRTPKCSHVCQSGYTVDYAKDKHFGSKSYSVRRNVRE 244
            |||:.::        ||......:   |....||.:        |..|.|.:.:....| .|:.|
Worm    26 SPCQENILSHEFIKKNGVVTEADYPYVGKENEKCKY--------DENKIKLWPTNMLLV-GNLPE 81

  Fly   245 --IQEEIMTNGPVEGAFTVYEDLILYKDGVY---QHEHGKELGGHAIRILGWGVWGEEKIPYWLI 304
              ::..|..:||.............||.|:|   |.|.||.....::.|:|:|:.|.:.  ||::
Worm    82 TLLKLFIKEHGPGYFRMKAPPSFFNYKTGIYSPTQEECGKATDARSLTIVGYGIEGGQN--YWIV 144

  Fly   305 GNSWNT 310
            ..|:.|
Worm   145 KGSFGT 150

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CtsB1	NP_001259536.2	Propeptide_C1	24..64	CDD:285358
CtsB1	NP_001259536.2	Peptidase_C1A_CathepsinB	88..336	CDD:239111	33/136 (24%)
C32B5.13	NP_493866.1	Peptidase_C1	1..150	CDD:390061	32/134 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161100
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830