Protein Alignment CtsB and cpr-6

DIOPT Version :10

• Sequence 1: NP_572920.1
• Gene: CtsB / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_741818.1
• Gene: cpr-6 / 180931
• WormBaseID: WBGene00000786
• Length: 379
• Species: Caenorhabditis elegans
• Alignment Length: 336
• Identity: 168/336 - (50%)
• Similarity: 211/336 - (62%)
• Gaps: 21/336 - (6%)

  Fly    16 LTSGEPSLLSDEFIEVVRSKAKTWTV--GRNFDASVTEGHIRR--LMGVHPDAHKFALPDKREVL 76
            :.|....|..|:.|:.|......||.  .|.|.:...|....:  ||||:   |.     :..|.
 Worm    34 IDSEAAELDGDDLIDYVNENQNLWTAKKQRRFSSVYGENDKAKWGLMGVN---HV-----RLSVK 90

  Fly    77 GDLYVNSVDEL----PEEFDSRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVN 137
            |..:::...:|    ||.||||..||.|.:|..||||.|||||||||||||||||:||.|.|::.
 Worm    91 GKQHLSKTKDLDLDIPESFDSRDNWPKCDSIKVIRDQSSCGSCWAFGAVEAMSDRICIASHGELQ 155

  Fly   138 FHFSADDLVSCCHTCGFGCNGGFPGAAWSYWTRKGIVSGGPYGSNQGCRPYEISPCEHHVNGTR- 201
            ...|||||:|||.:||||||||.|.|||.||.:.|||:|..|.:|.||:||...|||||...|.
 Worm   156 VTLSADDLLSCCKSCGFGCNGGDPLAAWRYWVKDGIVTGSNYTANNGCKPYPFPPCEHHSKKTHF 220

  Fly   202 PPCAHG-GRTPKCSHVCQSGYT-VDYAKDKHFGSKSYSVRRNVREIQEEIMTNGPVEGAFTVYED 264
            .||.|. ..||||...|.|.|| ..|::||.||:.:|.|:.:|..||:|:||:||:|.||.||||
 Worm   221 DPCPHDLYPTPKCEKKCVSDYTDKTYSEDKFFGASAYGVKDDVEAIQKELMTHGPLEIAFEVYED 285

  Fly   265 LILYKDGVYQHEHGKELGGHAIRILGWGVWGEEKIPYWLIGNSWNTDWGDHGFFRILRGQDHCGI 329
            .:.|..|||.|..||..||||::::|||:  ::.||||.:.||||||||:.||||||||.|.|||
 Worm   286 FLNYDGGVYVHTGGKLGGGHAVKLIGWGI--DDGIPYWTVANSWNTDWGEDGFFRILRGVDECGI 348

  Fly   330 ESSISAGLPKL 340
            ||.:..|:|||
 Worm   349 ESGVVGGIPKL 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB	NP_572920.1	Propeptide_C1	24..64	CDD:462365	12/43 (28%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	146/250 (58%)
cpr-6	NP_741818.1	Peptidase_C1A_CathepsinB	106..355	CDD:239111	146/250 (58%)