Protein Alignment CtsB1 and Y51A2D.1

DIOPT Version :9

• Sequence 1: NP_001259536.2
• Gene: CtsB1 / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001256811.1
• Gene: Y51A2D.1 / 180204
• WormBaseID: WBGene00013072
• Length: 314
• Species: Caenorhabditis elegans
• Alignment Length: 355
• Identity: 81/355 - (22%)
• Similarity: 120/355 - (33%)
• Gaps: 137/355 - (38%)

  Fly    17 TSGEPSLLSDEFIE----VVRSKAKTWTVGRN--------FDASVTEGHIRRLMGVHPDAHKFAL 69
            :..|..|....|::    |||........|||        .|.:.:|.| :||....|:..:.::
 Worm    57 SEAENQLRLQNFVKSRNNVVRLNKNAQKAGRNSNFAVNQFSDLTTSELH-QRLSRFPPNLTENSV 120

  Fly    70 PDK--REVLGDLYV---NSVDELPEEFDSRKQWPNCP-TIGEIRDQGSCGSCWAFGAVEAMSDRV 128
            ..|  :::||....   ||  |....||.|.|..|.. .:|.|::||.|..||.| ||.||.:.:
 Worm   121 FHKNFKKLLGKTRTKRQNS--EFARNFDLRSQKVNGRYIVGPIKNQGQCACCWGF-AVTAMLETI 182

  Fly   129 CIHSGG----KVNFHFSADDLVSCCHTCGFGCNGGFPGAAWSYWTRKGIVSGGPYGSNQGCRPYE 189
            ...:.|    |:::||
 Worm   183 YAVNVGRFKRKLDYHF------------------------------------------------- 198

  Fly   190 ISPCEHHVNGTRPPCAHGGRTPKCSHVCQSGYTVDYAKDKHFGSKSYSVRRNVREIQEEIMT-NG 253
                      .||..|..                                    ||.|.:.| ..
 Worm   199 ----------IRPENAES------------------------------------EIIEILNTWKT 217

  Fly   254 PVEGAFTVYEDLILYKDGVYQHEHGKELGG---HAIRILGWGVWGEE------KIPYWLIGNSWN 309
            ||...|......:.||.||...| ..:|.|   ||..|:|   :|||      ...:|::.|||.
 Worm   218 PVAVYFAAGTAFLQYKSGVLVTE-DCDLAGTVWHAGAIVG---YGEENDLRGRSQRFWIMKNSWG 278

  Fly   310 -TDWGDHGFFRILRGQDHCGIE-SSISAGL 337
             :.||..|:.:::||::.|||| .:|.|.:
 Worm   279 VSGWGTGGYVKLIRGKNWCGIERGAIGANM 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB1	NP_001259536.2	Propeptide_C1	24..64	CDD:285358	13/51 (25%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	59/264 (22%)
Y51A2D.1	NP_001256811.1	Inhibitor_I29	44..103	CDD:214853	10/45 (22%)
		Peptidase_C1A	144..303	CDD:239068	58/258 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161065
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940