Protein Alignment CtsB and tag-196

DIOPT Version :10

• Sequence 1: NP_572920.1
• Gene: CtsB / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_505215.2
• Gene: tag-196 / 179240
• WormBaseID: WBGene00007055
• Length: 477
• Species: Caenorhabditis elegans
• Alignment Length: 266
• Identity: 71/266 - (26%)
• Similarity: 119/266 - (44%)
• Gaps: 52/266 - (19%)

  Fly    78 DLYVNSVDELPEEFDSRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSA 142
            |:.:|. ::|||.||    |.....:.::::||:|||||||.....:.....|.....|:  .|.
 Worm   256 DVTINE-EDLPESFD----WREKGAVTQVKNQGNCGSCWAFSTTGNVEGAWFIAKNKLVS--LSE 313

  Fly   143 DDLVSCCHTCGFGCNGGFPGAAWSYWTRKGIVSGGPYGSNQGCRPYEISPCEHHVNGTRPPCAHG 207
            .:||. |.:...|||||.|..|:....|.|           |..|.:..|             :.
 Worm   314 QELVD-CDSMDQGCNGGLPSNAYKEIIRMG-----------GLEPEDAYP-------------YD 353

  Fly   208 GRTPKCSHVCQSGYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNGPVEGAFTVYEDLILYKDGV 272
            ||...| |:.:....|       :.:.|..:..:..|:|:.::|.||:...... ..|..|:.||
 Worm   354 GRGETC-HLVRKDIAV-------YINGSVELPHDEVEMQKWLVTKGPISIGLNA-NTLQFYRHGV 409

  Fly   273 YQHEHGKELG------GHAIRILGWGVWGEEKIPYWLIGNSWNTDWGDHGFFRILRGQDHCGIES 331
            .   |..::.      .|.:.|:|:|..|.:  |||::.|||..:||:.|:|::.||::.||::.
 Worm   410 V---HPFKIFCEPFMLNHGVLIVGYGKDGRK--PYWIVKNSWGPNWGEAGYFKLYRGKNVCGVQE 469

  Fly   332 SISAGL 337
            ..::.|
 Worm   470 MATSAL 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB	NP_572920.1	Propeptide_C1	24..64	CDD:462365
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	67/253 (26%)
tag-196	NP_505215.2	CY	23..>91	CDD:447698
		Inhibitor_I29	174..231	CDD:462410
		Peptidase_C1	264..475	CDD:425470	68/255 (27%)