Protein Alignment CtsB and W07B8.4

DIOPT Version :10

• Sequence 1: NP_572920.1
• Gene: CtsB / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_503382.1
• Gene: W07B8.4 / 178611
• WormBaseID: WBGene00021072
• Length: 335
• Species: Caenorhabditis elegans
• Alignment Length: 344
• Identity: 157/344 - (45%)
• Similarity: 204/344 - (59%)
• Gaps: 28/344 - (8%)

  Fly     5 LLVATAASVAALTSGEPSLLSDEFIEVVRSKAKTWTVGRNFDASVTEGHIRRLMGV-HPDAHKFA 68
            ||...|||...|...:      .||..:.|..|.||.    :...|...::.||.| |..||.
 Worm     8 LLFILAASAVVLPRNK------LFINHINSAQKLWTA----EHYTTPFEVKNLMKVEHVAAHL-- 60

  Fly    69 LPDKREVLGDLYVNSVDELPEEFDSRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSG 133
              ||...|.:    :.|.:|:.:|.|..||.|.::..||||..||||||..|.||:|||.||.|.
 Worm    61 --DKDIKLAE----TADSIPDSYDVRDHWPQCISVNNIRDQSHCGSCWAVAAAEAISDRTCIASN 119

  Fly   134 GKVNFHFSADDLVSCC---HTCGFGCNGGFPGAAWSYWTRKGIVSGGPYGSNQGCRPYEISPCEH 195
            |.||...||:|:::||   ..||.||.||:|..||.||.:.|:|:||.:.|..||:||.|:||..
 Worm   120 GDVNTLLSAEDILTCCTGKFNCGDGCEGGYPIQAWRYWVKNGLVTGGSFESQYGCKPYSIAPCGE 184

  Fly   196 HVNG-TRPPCAHG-GRTPKCSHVC--QSGYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNGPVE 256
            .::| |.|.|... ..||||.|.|  .:.|.:.|.:|||||:.:|::.|:.::||.||:.:||||
 Worm   185 TIDGVTWPECPMKISDTPKCEHHCTGNNSYPIPYDQDKHFGASAYAIGRSAKQIQTEILAHGPVE 249

  Fly   257 GAFTVYEDLILYKDGVYQHEHGKELGGHAIRILGWGVWGEEKIPYWLIGNSWNTDWGDHGFFRIL 321
            ..|.||||..|||.|:|.|..|.||||||:::|||||  :...||||..|||||.||:.|:||||
 Worm   250 VGFIVYEDFYLYKTGIYTHVAGGELGGHAVKMLGWGV--DNGTPYWLAANSWNTVWGEKGYFRIL 312

  Fly   322 RGQDHCGIESSISAGLPKL 340
            ||.|.|||||:..||:|.|
 Worm   313 RGVDECGIESAAVAGMPDL 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB	NP_572920.1	Propeptide_C1	24..64	CDD:462365	11/40 (28%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	130/254 (51%)
W07B8.4	NP_503382.1	Peptidase_C1A_CathepsinB	74..327	CDD:239111	130/254 (51%)