Protein Alignment CtsB and F26E4.3

DIOPT Version :10

• Sequence 1: NP_572920.1
• Gene: CtsB / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_492593.2
• Gene: F26E4.3 / 172827
• WormBaseID: WBGene00009158
• Length: 452
• Species: Caenorhabditis elegans
• Alignment Length: 334
• Identity: 115/334 - (34%)
• Similarity: 166/334 - (49%)
• Gaps: 48/334 - (14%)

  Fly    19 GEPSLLSDEFIEVVRSKAKTWTVGRNFDA----SVTEGHIRRLMGVHPDAHKFALPDKREVLGDL 79
            |...|:..:.:|.:.:...:|: .||:.|    |:::|...||..:.|:.   ::.:..|:|
 Worm   121 GTACLIQPDILEKIHTGRYSWS-ARNYSAFWGRSLSDGIKYRLGTLFPER---SVQNMNEIL--- 178

  Fly    80 YVNSVDELPEEFDSRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSADD 144
              ....||||.||:|.:|.  |.|..:.|||.|||.|:.......|||:.|.|.|::|...|:..
 Worm   179 --IKPRELPEHFDARDKWG--PLIHPVADQGDCGSSWSVSTTAISSDRLAIISEGRINSTLSSQQ 239

  Fly   145 LVSCCHTCGFGCNGGFPGAAWSYWTRKGIVSGG--PYGSNQGCRP-YEISPCEHHVN--GTRPPC 204
            |:||......||.||:...||.|..:.|:|...  ||.|.|...| :.:.|...:.|  |.|
 Worm   240 LLSCNQHRQKGCEGGYLDRAWWYIRKLGVVGDHCYPYVSGQSREPGHCLIPKRDYTNRQGLR--- 301

  Fly   205 AHGGRTPKCSHVCQSGYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNGPVEGAFTVYEDLILYK 269
                        |.|| :.|....|.  :..|.|.....:||.|:||||||:..|.|:||..:|.
 Worm   302 ------------CPSG-SQDSTAFKM--TPPYKVSSREEDIQTELMTNGPVQATFVVHEDFFMYA 351

  Fly   270 DGVYQH-----EHGKEL---GGHAIRILGWGVWGE--EKIPYWLIGNSWNTDWGDHGFFRILRGQ 324
            .|||||     :.|...   |.|::|:|||||...  :.|.|||..|||.|.||:.|:|::|||:
 Worm   352 GGVYQHSDLAAQKGASSVAEGYHSVRVLGWGVDHSTGKPIKYWLCANSWGTQWGEDGYFKVLRGE 416

  Fly   325 DHCGIESSI 333
            :||.|||.:
 Worm   417 NHCEIESFV 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB	NP_572920.1	Propeptide_C1	24..64	CDD:462365	10/43 (23%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	99/261 (38%)
F26E4.3	NP_492593.2	Somatomedin_B	37..83	CDD:460034
		Peptidase_C1A_CathepsinB	185..428	CDD:239111	99/261 (38%)