Protein Alignment CtsB1 and Ctss

DIOPT Version :9

• Sequence 1: NP_001259536.2
• Gene: CtsB1 / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001254624.2
• Gene: Ctss / 13040
• MGIID: 107341
• Length: 341
• Species: Mus musculus
• Alignment Length: 303
• Identity: 87/303 - (28%)
• Similarity: 133/303 - (43%)
• Gaps: 52/303 - (17%)

  Fly    38 TWTVGRNFDASVTEGHIRRLMGVHPDAHKFALPDKREVLGDLYVNSVDELPEEFDSRKQWPNCPT 102
            |:.||.|....:|...|...||    |.:......:.|....|.|..  ||:..|.|::  .|.|
Mouse    81 TYQVGMNDMGDMTNEEILCRMG----ALRIPRQSPKTVTFRSYSNRT--LPDTVDWREK--GCVT 137

  Fly   103 IGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSADDLVSCCHTCGF---GCNGGFPGAA 164
              |::.|||||:||||.||.|:..::.:.:|..::  .||.:||.|.:...:   ||.||:...|
Mouse   138 --EVKYQGSCGACWAFSAVGALEGQLKLKTGKLIS--LSAQNLVDCSNEEKYGNKGCGGGYMTEA 198

  Fly   165 WSYWTRKGIVSGGPYGSNQGCRPYEISPCEHHVNGTRPPCAHGGRTPKCSHVCQSGYTVDYAKDK 229
            :.|     |:..|...:: ...||:.:..:.|.|..       .|...||...|          .
Mouse   199 FQY-----IIDNGGIEAD-ASYPYKATDEKCHYNSK-------NRAATCSRYIQ----------L 240

  Fly   230 HFGSKSYSVRRNVREIQEEIMTNGPVE-GAFTVYEDLILYKDGVYQHEHGKELGGHAIRILGWGV 293
            .||.:.        .::|.:.|.|||. |....:.....||.|||..........|.:.::|:|.
Mouse   241 PFGDED--------ALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTGNVNHGVLVVGYGT 297

  Fly   294 W-GEEKIPYWLIGNSWNTDWGDHGFFRILR-GQDHCGIESSIS 334
            . |::   |||:.|||..::||.|:.|:.| .::||||.|..|
Mouse   298 LDGKD---YWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCS 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB1	NP_001259536.2	Propeptide_C1	24..64	CDD:285358	8/25 (32%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	74/253 (29%)
Ctss	NP_001254624.2	Inhibitor_I29	37..96	CDD:214853	5/14 (36%)
		Peptidase_C1	124..339	CDD:278538	75/254 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820