Protein Alignment CtsB1 and Ctsh

DIOPT Version :9

• Sequence 1: NP_001259536.2
• Gene: CtsB1 / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_031827.2
• Gene: Ctsh / 13036
• MGIID: 107285
• Length: 333
• Species: Mus musculus
• Alignment Length: 342
• Identity: 86/342 - (25%)
• Similarity: 134/342 - (39%)
• Gaps: 80/342 - (23%)

  Fly    25 SDEFIEVVRSKAKTWTVGRNFDASVTEGHIRRL-------MGVHPDAHKF--ALPDKREVLGDLY 80
            |.|:...::..|..|   |...|.....|..::       |......|||  :.|.........|
Mouse    46 SVEYNHRLQMFANNW---RKIQAHNQRNHTFKMALNQFSDMSFAEIKHKFLWSEPQNCSATKSNY 107

  Fly    81 VNSVDELPEEFDSRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSADDL 145
            :......|...|.||:.   ..:..:::||:|||||.|....|:...|.|.||..::  .:...|
Mouse   108 LRGTGPYPSSMDWRKKG---NVVSPVKNQGACGSCWTFSTTGALESAVAIASGKMLS--LAEQQL 167

  Fly   146 VSCCHTC-GFGCNGGFPGAAWSY-WTRKGIVSGGPY---GSNQGCRPYEISPCEHHVNGTRPPCA 205
            |.|.... ..||.||.|..|:.| ...|||:....|   |.:..||   .:|
Mouse   168 VDCAQAFNNHGCKGGLPSQAFEYILYNKGIMEEDSYPYIGKDSSCR---FNP------------- 216

  Fly   206 HGGRTPKCSHVCQSGYTVDYAKDKHFGSKSYSVRRNVREIQ--------EEIMTNGPVEGAFTVY 262
                                       .|:.:..:||..|.        |.:....||..||.|.
Mouse   217 ---------------------------QKAVAFVKNVVNITLNDEAAMVEAVALYNPVSFAFEVT 254

  Fly   263 EDLILYKDGVYQ----HEHGKELGGHAIRILGWGVWGEEKIPYWLIGNSWNTDWGDHGFFRILRG 323
            ||.::||.|||.    |:...:: .||:..:|:|  .:..:.||::.|||.:.||::|:|.|.||
Mouse   255 EDFLMYKSGVYSSKSCHKTPDKV-NHAVLAVGYG--EQNGLLYWIVKNSWGSQWGENGYFLIERG 316

  Fly   324 QDHCGIESSISAGLPKL 340
            ::.||:.:..|..:|::
Mouse   317 KNMCGLAACASYPIPQV 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB1	NP_001259536.2	Propeptide_C1	24..64	CDD:285358	8/45 (18%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	72/264 (27%)
Ctsh	NP_031827.2	Inhibitor_I29	33..88	CDD:285458	8/44 (18%)
		Peptidase_C1	115..330	CDD:278538	72/265 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820