Protein Alignment CtsB and Swim

DIOPT Version :10

• Sequence 1: NP_572920.1
• Gene: CtsB / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: XP_061500477.1
• Gene: Swim / 1269545
• VectorBaseID: AGAMI1_006202
• Length: 471
• Species: Anopheles gambiae
• Alignment Length: 346
• Identity: 101/346 - (29%)
• Similarity: 148/346 - (42%)
• Gaps: 60/346 - (17%)

  Fly    15 ALTSGEPSLLSDEFI-----EVVRS---KAKTWTV--GRNFDASVTEGHIRRLMGVHPDAHKFAL 69
            ::|..|...|:|:.:     .:.||   ||..::.  |..:|    ||.:.||....|   :|.:
Mosquito   125 SVTCTEDVCLADDDLLRQLHHLERSIGWKATNYSEWWGHKYD----EGKVLRLGTFQP---RFRV 182

  Fly    70 PDKREVLGDLYVNSVDELPEEFDSRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGG 134
            ...:.:     .|....||..||:.:.|..  .:.|.||||.|||.|||......|||..|.|.|
Mosquito   183 KAMKRL-----SNKGGHLPSRFDASEHWTG--LVAEARDQGWCGSSWAFSTATMASDRFAILSKG 240

  Fly   135 KVNFHFSADDLVSCCHTCGFGCNGGFPGAAWSYWTRKGIVSGGPYGSNQGCRPYEISP--CEHHV 197
            :.....:...:::|... ..||:||....||.|..|.|:|       |:.|.||..:.  |:...
Mosquito   241 REMVQLAPQQMLACVRR-QQGCSGGHLDTAWQYLRRTGVV-------NEECYPYIAAQNVCKISN 297

  Fly   198 NGTRPPCAHGGRTPKCSHVCQSGYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNGPVEGAFTVY 262
            :.|.       .|..|....:...|:.|.....|.      ..|..:|..||...|.|:....||
Mosquito   298 DDTL-------ITANCELPVKVNRTLMYKMGPAFS------LNNETDIMAEIKDRGTVQAIMRVY 349

  Fly   263 EDLILYKDGVYQHEHG-----KELGGHAIRILGWGVWGEEK-----IPYWLIGNSWNTDWGDHGF 317
            .|...|:.|:|:|...     :....|::|::|   ||||:     :.||:..|||...||::|.
Mosquito   350 RDFFSYRSGIYRHSAAATPAEERSAYHSVRLIG---WGEERVGYDVVKYWIAINSWGQWWGENGR 411

  Fly   318 FRILRGQDHCGIESSISAGLP 338
            ||||||.:.|.|||.:.|..|
Mosquito   412 FRILRGSNECDIESYVLASNP 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB	NP_572920.1	Propeptide_C1	24..64	CDD:462365	13/49 (27%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	81/259 (31%)
Swim	XP_061500477.1	None