Protein Alignment CtsB1 and AgaP_AGAP012577

DIOPT Version :9

• Sequence 1: NP_001259536.2
• Gene: CtsB1 / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: XP_307325.4
• Gene: AgaP_AGAP012577 / 1268756
• VectorBaseID: AGAP012577
• Length: 547
• Species: Anopheles gambiae
• Alignment Length: 337
• Identity: 81/337 - (24%)
• Similarity: 121/337 - (35%)
• Gaps: 107/337 - (31%)

  Fly    28 FIEVVRSKAKTWTVGRNFDASVTEGHIR-----RLMGVHPDAHKFALPDKREVLGDLYVNSVDEL 87
            ||.......:.:||..|..|..||..::     |..|.:.....|.....:.:.         :|
Mosquito   274 FIHSHNRANRGFTVAVNHLADRTEEELKALRGFRSSGTYNGGQPFPYDTPKHMA---------DL 329

  Fly    88 PEEFDSRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGG------KVNFHFSADDLV 146
            |:.:|    |.....:..::||..|||||:||.:.        |..|      :....||...|:
Mosquito   330 PDSWD----WRISGAVTPVKDQSVCGSCWSFGTIG--------HIEGAYFRKTQKLVRFSQQALI 382

  Fly   147 SCCHTCGF---GCNGGFPGAAWSYWTRKGIVS-----GGPYGSNQGCRPYEI---SPCEHHVNGT 200
            .|  :.|:   ||:||....|:.:....|.|.     ||..|.:..|....:   :|....||.|
Mosquito   383 DC--SWGYGNNGCDGGEDFRAYQWMMEVGGVPMEDEYGGYLGQDGYCHVQNMTLYAPITGWVNVT 445

  Fly   201 R-PPCA-------HGGRTPKCSHVCQSGYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNGPVEG 257
            . .|.|       ||              .:..|.|.  |.||:|
Mosquito   446 SGDPDAFKLALFKHG--------------PLSIAIDA--GHKSFS-------------------- 474

  Fly   258 AFTVYEDLILYKDGVYQHEHGK----ELGGHAIRILGWG-VWGEEKIPYWLIGNSWNTDWGDHGF 317
                     .|.:|||.....|    || .||:..:|:| :.||:   ||||.|||:..||:.|:
Mosquito   475 ---------FYSNGVYYEPECKNKLDEL-DHAVLAVGYGQLNGED---YWLIKNSWSNYWGNDGY 526

  Fly   318 FRILRGQDHCGI 329
            ..:....::||:
Mosquito   527 ALMAVKDNNCGL 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB1	NP_001259536.2	Propeptide_C1	24..64	CDD:285358	10/40 (25%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	69/272 (25%)
AgaP_AGAP012577	XP_307325.4	Inhibitor_I29	244..299	CDD:214853	8/24 (33%)
		Peptidase_C1	329..546	CDD:278538	70/273 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910