DRSC/TRiP Functional Genomics Resources

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Protein Alignment CtsB1 and Cts3

DIOPT Version :9

Sequence 1:NP_001259536.2 Gene:CtsB1 / 32341 FlyBaseID:FBgn0030521 Length:340 Species:Drosophila melanogaster
Sequence 2:NP_081182.2 Gene:Cts3 / 117066 MGIID:2151929 Length:332 Species:Mus musculus


Alignment Length:246 Identity:61/246 - (24%)
Similarity:96/246 - (39%) Gaps:51/246 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    97 WPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSADDLVSCCHTCGFGCNGGFP 161
            |.....:..:|.|.:|.||||.....|:..::...:|..:  ..|..:||.|..  |.||:.|..
Mouse   120 WKKRGYVTPVRTQIACNSCWAISVTGAIEGQMFRKTGQLI--PLSVQNLVDCVD--GSGCHAGSV 180

  Fly   162 GAAWSYWTRKGIVSGG---PYGSNQG-CRPYEISPCEHHVNGTRPPCAHGGRTPKCSHVCQSGYT 222
            ..::.|...||.:...   ||...|| ||                      ..|:.|....:|:.
Mouse   181 LDSFKYLMEKGGLESEATYPYEDKQGSCR----------------------YNPENSTASITGFE 223

  Fly   223 VDYAKDKHFGSKSYSVRRNVREIQEEIMTNGPVEGAFTV-YEDLILYKDGVYQHEH-GKELGG-- 283
            .              :..|..::...:.:.||:...... :|..:.||.|:|...: ...|..  
Mouse   224 F--------------IPNNEVDLMSAVASLGPISVVIDAWHESFLFYKRGIYYEPNCNNSLFALR 274

  Fly   284 HAIRILGWGVWGEEK--IPYWLIGNSWNTDWGDHGFFRILRGQ-DHCGIES 331
            ||:.::|:|..|.|.  ..||:|.||..|.||..|:.:|.:.| :||||.|
Mouse   275 HAVLLVGYGFIGRESEGRKYWIIKNSLGTKWGYKGYMKIAKDQGNHCGIAS 325

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CtsB1NP_001259536.2 Propeptide_C1 24..64 CDD:285358
Peptidase_C1A_CathepsinB 88..336 CDD:239111 61/246 (25%)
Cts3NP_081182.2 Inhibitor_I29 29..87 CDD:214853
Peptidase_C1A 115..330 CDD:239068 61/246 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG4870
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53545
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.820

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