DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CtsB1 and LOC100333521

DIOPT Version :9

Sequence 1:	NP_001259536.2	Gene:	CtsB1 / 32341	FlyBaseID:	FBgn0030521	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	XP_002661007.2	Gene:	LOC100333521 / 100333521	-ID:	-	Length:	301	Species:	Danio rerio

Alignment Length:	277	Identity:	82/277 - (29%)
Similarity:	118/277 - (42%)	Gaps:	48/277 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 YVNSVDELPEEFDSRKQWPNCP---TIGEIRDQ---GSCGSCWAFGAVEAMSDRVCI-HSGGKVN 137
            |:| |.:||..:|    |.|..   .:...|:|   ..||||||.|:..|::||:.| ..|...:
Zfish    52 YLN-VSDLPASWD----WRNIDGKNYVSITRNQHIPQYCGSCWAMGSTSALADRINIKRKGAWPS 111

  Fly   138 FHFSADDLVSCCHTCGFGCNGGFPGAAWSYWTRKGI---VSGGPYGSNQGCRPYEISPCEHHVNG 199
            .:.|..:::. |...| .|.||.....::|....||   ........||.|.|:  :.|     |
Zfish   112 AYLSVQNVID-CGKAG-SCFGGDHLGVYAYANEHGIPDETCNNYQARNQKCDPF--NQC-----G 167

  Fly   200 TRPPCAHGGRTPKCSHVCQSGYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNGPVEGAFTVYED 264
            |   |:..|   .||.:  ..|||....|  :|..|...|     ::.||..|||:..|....:.
Zfish   168 T---CSFFG---SCSII--KNYTVWKVGD--YGDISGRDR-----MKAEIFKNGPISCAIMATKG 217

  Fly   265 LILYKDGVYQHEHGKELGGHAIRILGWGVWGEEKIPYWLIGNSWNTDWGDHGFFRILRGQDHCG- 328
            |..|..||:...|...:..|.|.:.|||| .|:...||::.|||...||:.|:.||:......|
Zfish   218 LEAYDGGVFAEFHILSMPNHIISVAGWGV-TEDGTEYWIVRNSWGEFWGESGWARIVTSAYKGGK 281

  Fly   329 -------IESSISAGLP 338
                   ||:..:.|.|
Zfish   282 GNWYNVAIENDCAYGDP 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CtsB1	NP_001259536.2	Propeptide_C1	24..64	CDD:285358
CtsB1	NP_001259536.2	Peptidase_C1A_CathepsinB	88..336	CDD:239111	76/265 (29%)
LOC100333521	XP_002661007.2	Peptidase_C1A_CathepsinX	58..299	CDD:239149	79/270 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910