Protein Alignment rdgB and Lpin2

DIOPT Version :10

• Sequence 1: NP_001259535.1
• Gene: rdgB / 32340
• FlyBaseID: FBgn0003218
• Length: 1297
• Species: Drosophila melanogaster
• Sequence 2: NP_001158357.1
• Gene: Lpin2 / 64898
• MGIID: 1891341
• Length: 931
• Species: Mus musculus
• Alignment Length: 1039
• Identity: 175/1039 - (16%)
• Similarity: 302/1039 - (29%)
• Gaps: 389/1039 - (37%)

  Fly   241 QDEWFGLTIEDIRELERQTQLALAKKMGGGEECSDDSVSEPYVSTAA-TAASTTGSERKKSAPAV 304
            :|::|           :..:..|.|..|.........||....|.|. |.:|....:|::.
Mouse   149 EDQFF-----------KHIETPLVKSSGNERPAQSSDVSHTLESEAVFTQSSVKKKKRRRK---- 198

  Fly   305 PPIVTQQPPSAEASSDEEGEEEEDDD--EDENDAIGTGVDLSANQGGSAQRSRSQSIQMAQKGKF 367
                       :...|...||:....  ||..|     |.:|::....||.:|..|....::..:
Mouse   199 -----------KCKQDNRKEEQAASPVAEDVGD-----VGVSSDDEKRAQAARGSSNASLKEEDY 247

  Fly   368 GSKGALHS----PVGSAHSFDLQSKKPHAKTAPRRHVANWRMERLEVDSKSNSDEEFFDCLDTNE 428
            ......||    |:.......|::..|.|                 |..||:|:      |:...
Mouse   248 KEPSLFHSGDNYPLSDGDWSPLETTYPQA-----------------VCPKSDSE------LEVKP 289

  Fly   429 TNSLAKWSSLELLGEGDDSPPPH------GGPSSAASVGGRGNSRQEDSIFNQDFLMRVASERGN 487
            :.||.:             ..||      |.|.|.                           :..
Mouse   290 SESLLR-------------SEPHMEWTWGGFPEST---------------------------KVT 314

  Fly   488 KRQLRSSASVDRSHDSSPPGSPSTPSCPTTILILVVHAGSVLDAASELTAKKSDVTTFRGSFEAV 552
            ||:         .:|..|..:..|||..|...::......:.:...:.|.:.:..|..:....|:
Mouse   315 KRE---------RYDYHPRTATITPSENTHFRVIPSEDSLIREVEKDATVEDTTCTIVKPKPRAL 370

  Fly   553 MRQHYPSLLTHVTIKMVPCPSICT--DALGILSSLSPYSFDASPSAADIPNIA------------ 603
            .:|...:..|.:....:..|.|.:  ||..:.|..:....:..|:|.|.|...
Mouse   371 CKQLSDAASTELPESPLEAPQISSLLDADPVPSPSAEAPSEPKPAAKDSPTKKKGVHKRSQHQGP 435

  Fly   604 -DVPIGAIPLLSVASPEFHETVNKTVAAANIVYHEFLKSE---------EGHGFSGQIVMLGDSM 658
             |:.:..:..|   .||        |||   :|  |.||:         |...|||
Mouse   436 DDIYLDDLKAL---EPE--------VAA---LY--FPKSDTDPGSRQWPESDTFSG--------- 475

  Fly   659 GSLLAYEALCRSNGSQPGTASGASNSGGDAATNINTHNPLSPRNSRLDDDERFIEADLDAKRLLV 723
                        :.|.....|.|::||.:.                |.|.    ..||....|.:
Mouse   476 ------------SQSPQSVGSAAADSGTEC----------------LSDS----AMDLPDVTLSL 508

  Fly   724 APSPRRRRSSSSSDSRATKLDFEVCDFFMFGSPLSVVLAARKLHDAKAALPRPN-CHQVYNLFHP 787
            .       ...|.:...:|..|           :..::...:..:....:..|| ..::||.::
Mouse   509 C-------GGLSENGEISKEKF-----------MEHIITYHEFAENPGLIDNPNLVIRIYNRYY- 554

  Fly   788 TDPIASRLEPLLSARFSILAPVNVPRYAKYPLGNGQPLHLLEVIQSHPQHFNDGNNLLAGRRLSD 852
                          .:::.||:               :..|:|.|               :.|..
Mouse   555 --------------NWALAAPM---------------ILSLQVFQ---------------KSLPK 575

  Fly   853 ASMQSTISGLIENVSLSTIHALQNKWWGTKRLDYALYCPEGLSNFPAHALPHLFHASYWESPDVI 917
            |:::|.:...:...|        .:||                              :|...:
Mouse   576 ATVESWVKDKMPKKS--------GRWW------------------------------FWRKKE-- 600

  Fly   918 AFILRQI-----GKFEGIPFVGSNDDKDNASFHPGQPREKWIKKRTSVKLKNVAANHRANDVIVQ 977
             .:::|:     ||.|..|   :||...||.    :|               .:|....||....
Mouse   601 -SMIKQLPETKEGKSEVPP---ANDLPSNAE----EP---------------TSARPAENDTSSD 642

  Fly   978 EGREQRLNARFMYGPLDMITLHGEKVDVHIMKDPPAGEWTFLSTEVTDKNGRISYSIPDQVSLGY 1042
            || .|.|.......|:.:.||                  :...|....|:.|:|.....::.|..
Mouse   643 EG-SQELEESIKVDPITVETL------------------SHCGTASYKKSLRLSSDQIAKLKLHD 688

  Fly  1043 G----IYPVKMVVRGDHTSVDCYMAVVPPL----TECVVFSIDGSFTAS------MSVTGRDPKV 1093
            |    ::.:....:|     .|..|....|    .:.::..|||:.|.|      :...|:| ..
Mouse   689 GPNDVVFSITTQYQG-----TCRCAGTIYLWNWNDKVIISDIDGTITKSDALGQILPQLGKD-WT 747

  Fly  1094 RAGAVDVCRHWQELGYLLIYIT----GRPDMQQQRVVSWLSQHN--FPHGLISFA---------- 1142
            ..|...:.....|.||..:|.:    |..|| .:..:.|::...  .|.|.:..:
Mouse   748 HQGIARLYHSINENGYKFLYCSARAIGMADM-TRGYLHWVNDKGTILPRGPLMLSPSSLFSAFHR 811

  Fly  1143 DGLSTDPLGHKTAYLN---NLVQNHGISITAAYGS-SKDISVYTNVGMRTDQIFIVGKVGKKLQ 1202
            :.:...|...|...||   ||.........||:|: ..|:..||.||:...:||.|...|:.:|
Mouse   812 EVIEKKPEKFKIECLNDIKNLFAPSRQPFYAAFGNRPNDVYAYTQVGVPDCRIFTVNPKGELIQ 875

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdgB	NP_001259535.1	SRPBCC_PITPNM1-2_like	1..268	CDD:176898	4/26 (15%)
		DDHD	743..924	CDD:460725	17/181 (9%)
		LNS2	1072..1203	CDD:197870	37/157 (24%)
Lpin2	NP_001158357.1	Lipin_N	39..145	CDD:461356
		Lipin_mid	504..596	CDD:465292	19/192 (10%)
		LNS2	672..897	CDD:462403	46/211 (22%)