Protein Alignment rdgB and PITPNA

DIOPT Version :10

• Sequence 1: NP_001259535.1
• Gene: rdgB / 32340
• FlyBaseID: FBgn0003218
• Length: 1297
• Species: Drosophila melanogaster
• Sequence 2: NP_006215.1
• Gene: PITPNA / 5306
• HGNCID: 9001
• Length: 270
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 117/266 - (43%)
• Similarity: 169/266 - (63%)
• Gaps: 16/266 - (6%)

  Fly     1 MLIKEYRIPLPLTVEEYRIAQLYMIAKKSREESHGEGSGVEIIINEPY-KDGPGGNGQYTKKIYH 64
            :|:||||:.||::|:||::.|||.:|:.|:.|: |.|.|||:::|||| |||.  .||||.||||
Human     2 VLLKEYRVILPVSVDEYQVGQLYSVAEASKNET-GGGEGVEVLVNEPYEKDGE--KGQYTHKIYH 63

  Fly    65 VGNHLPGWIKSLLPKSALTVEEEAWNAYPYTRTRYTCPFV-EKFSLDIETYYYPDNGYQDNVFQL 128
            :.:.:|.:::.|.|:.||.:.|:|||||||.||..|..:: |.|.:.|||::.||.|.|:||.:|
Human    64 LQSKVPTFVRMLAPEGALNIHEKAWNAYPYCRTVITNEYMKEDFLIKIETWHKPDLGTQENVHKL 128

  Fly   129 SGSDLRNRIVDVIDIV-KDQLWGGDYVKEEDPKHFVSDKTGRGPLAEDWLEEYWREVKGKKQPTP 192
            .....::.....|||. :.|:...||..||||..|.|.|||||||..:|.:|.   |..|..|
Human   129 EPEAWKHVEAVYIDIADRSQVLSKDYKAEEDPAKFKSIKTGRGPLGPNWKQEL---VNQKDCP-- 188

  Fly   193 RNMSLMTAYKICRVEFRYWGMQTKLEKFIHDVALRKMMLRAHRQAWAWQDEWFGLTIEDIRELER 257
                .|.|||:..|:|::||:|.|:|.|||... |::....|||.:.|.|:|..||::|||.:|.
Human   189 ----YMCAYKLVTVKFKWWGLQNKVENFIHKQE-RRLFTNFHRQLFCWLDKWVDLTMDDIRRMEE 248

  Fly   258 QTQLAL 263
            :|:..|
Human   249 ETKRQL 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdgB	NP_001259535.1	SRPBCC_PITPNM1-2_like	1..268	CDD:176898	117/266 (44%)
		DDHD	743..924	CDD:460725
		LNS2	1072..1203	CDD:197870
PITPNA	NP_006215.1	SRPBCC_PITPNA-B_like	3..259	CDD:176897	117/265 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	250..270		2/5 (40%)