DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgB and pitpnc1b

DIOPT Version :9

Sequence 1:	NP_001259535.1	Gene:	rdgB / 32340	FlyBaseID:	FBgn0003218	Length:	1297	Species:	Drosophila melanogaster
Sequence 2:	XP_005157947.1	Gene:	pitpnc1b / 492803	ZFINID:	ZDB-GENE-041114-158	Length:	305	Species:	Danio rerio

Alignment Length:	320	Identity:	124/320 - (38%)
Similarity:	178/320 - (55%)	Gaps:	29/320 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLIKEYRIPLPLTVEEYRIAQLYMIAKKSREESHGEGSGVEIIINEPYKDGPGGNGQYTKKIYHV 65
            ||:|||||.:||||:||||.|||||:|.|.|:| |.|.|||::.|||..|...|:||.|:|..::
Zfish     1 MLVKEYRICMPLTVDEYRIGQLYMISKHSNEQS-GGGEGVEVVRNEPCTDPKHGSGQITEKRIYL 64

  Fly    66 GNHLPGWIKSLLPKSALTVEEEAWNAYPYTRTRYTCPFVEKFSLDIETYYYPDNGYQDNVFQLSG 130
            .:.||.|::..:| ....:.|.|||.||||.|.|||.|:.:|.:.|||::..|||...|||....
Zfish    65 NSKLPTWMRRFVP-MVFYLTETAWNFYPYTITEYTCSFLPRFHVKIETHFKNDNGCSKNVFGDDP 128

  Fly   131 SDLRNRIVDVIDIVKDQLWGGDYVKEEDPKHFVSDKTGRGPLAEDWLEEYWREVKGKKQPTPRNM 195
            :.:.|  |..:||:.|.:...:|.|.||...:||:|||||||.:.|        :...:|
Zfish   129 TPMDN--VCFLDILSDPIPEKNYKKSEDLSDWVSEKTGRGPLVDGW--------RNDTKP----- 178

  Fly   196 SLMTAYKICRVEFRYWGMQTKLEKFIHDVALRKMMLRAHRQAWAWQDEWFGLTIEDIRELERQTQ 260
             :|.:||.....|..:|.|.:.|.|:|. .:|.::|..||||.||.|||.|:|:|.:||.||:.|
Zfish   179 -IMCSYKRVTCSFEVYGFQGRTEDFVHR-NIRDILLVGHRQAVAWIDEWHGMTLEQVREFERKQQ 241

  Fly   261 LALAKKMGG--GEECSDDSVSEPYVSTAATAASTTGSERKKSAPAVPPIVTQQPPSAEAS 318
            .....|:..  ....||.::...:..:.:.   |..|..||..     :.|...||:::|
Zfish   242 EETNCKLKSDIASPGSDPAIRPSFTRSISV---TDESSLKKMG-----VTTLDIPSSQSS 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgB	NP_001259535.1	SRPBCC_PITPNM1-2_like	1..268	CDD:176898	114/266 (43%)
		DDHD	746..924	CDD:280937
		LNS2	1072..1203	CDD:197870
pitpnc1b	XP_005157947.1	SRPBCC	2..249	CDD:301327	113/265 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5083
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810