Protein Alignment rdgB and PITPNB

DIOPT Version :10

• Sequence 1: NP_001259535.1
• Gene: rdgB / 32340
• FlyBaseID: FBgn0003218
• Length: 1297
• Species: Drosophila melanogaster
• Sequence 2: XP_011528354.1
• Gene: PITPNB / 23760
• HGNCID: 9002
• Length: 274
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 106/283 - (37%)
• Similarity: 167/283 - (59%)
• Gaps: 16/283 - (5%)

  Fly     1 MLIKEYRIPLPLTVEEYRIAQLYMIAKKSREESHGEGSGVEIIINEPY-KDGPGGNGQYTKKIYH 64
            :|:::.|:.||.:|:||::.|||.:|:.|:.|: |.|.|:|::.|||| |||.  .||||.||||
Human     4 LLMEKCRVVLPCSVQEYQVGQLYSVAEASKNET-GGGEGIEVLKNEPYEKDGE--KGQYTHKIYH 65

  Fly    65 VGNHLPGWIKSLLPKSALTVEEEAWNAYPYTRTRYTCPFV-EKFSLDIETYYYPDNGYQDNVFQL 128
            :.:.:|.:::.:.|:.:|...|:|||||||.||..|..:: :.|.:.|||::.||.|..:||..|
Human    66 LKSKVPAFVRMIAPEGSLVFHEKAWNAYPYCRTIVTNEYMKDDFFIKIETWHKPDLGTLENVHGL 130

  Fly   129 SGSDLRNRIVDVIDIV-KDQLWGGDYVKEEDPKHFVSDKTGRGPLAEDWLEEYWREVKGKKQPTP 192
            ..:..:...:..|||. :.|:...||..:|||..|.|.||.||||..:|.:|.     ......|
Human   131 DPNTWKTVEIVHIDIADRSQVEPADYKADEDPALFQSVKTKRGPLGPNWKKEL-----ANSPDCP 190

  Fly   193 RNMSLMTAYKICRVEFRYWGMQTKLEKFIHDVALRKMMLRAHRQAWAWQDEWFGLTIEDIRELER 257
            :    |.|||:..::|::||:|:|:|.||.... :::....|||.:.|.|:|..||:||||.:|.
Human   191 Q----MCAYKLVTIKFKWWGLQSKVENFIQKQE-KRIFTNFHRQLFCWIDKWIDLTMEDIRRMED 250

  Fly   258 QTQLALAKKMGGGEECSDDSVSE 280
            :||..|......|:.....:.|:
Human   251 ETQKELETLRNQGQVRGTSAASD 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdgB	NP_001259535.1	SRPBCC_PITPNM1-2_like	1..268	CDD:176898	104/269 (39%)
		DDHD	743..924	CDD:460725
		LNS2	1072..1203	CDD:197870
PITPNB	XP_011528354.1	SRPBCC_PITPNA-B_like	10..261	CDD:176897	103/263 (39%)