DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgB and Pitpnb

DIOPT Version :9

Sequence 1:	NP_001259535.1	Gene:	rdgB / 32340	FlyBaseID:	FBgn0003218	Length:	1297	Species:	Drosophila melanogaster
Sequence 2:	XP_006249584.1	Gene:	Pitpnb / 114561	RGDID:	620143	Length:	272	Species:	Rattus norvegicus

Alignment Length:	283	Identity:	109/283 - (38%)
Similarity:	167/283 - (59%)	Gaps:	20/283 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLIKEYRIPLPLTVEEYRIAQLYMIAKKSREESHGEGSGVEIIINEPYKDGPGGNGQYTKKIYHV 65
            :||||:|:.||.:|:||::.|||.:|:.|:.|: |.|.|:|::.|||| :..|..||||.||||:
  Rat     2 VLIKEFRVVLPCSVQEYQVGQLYSVAEASKNET-GGGEGIEVLKNEPY-ENDGEKGQYTHKIYHL 64

  Fly    66 GNHLPGWIKSLLPKSALTVEEEAWNAYPYTRTRYTCPFV-EKFSLDIETYYYPDNGYQDNVFQLS 129
            .:.:|.:::.:.|:.:|...|:|||||||.||..|..:: :.|.:.|||::.||.|..:||..|.
  Rat    65 KSKVPAFVRMIAPEGSLVFHEKAWNAYPYCRTIVTNEYMKDDFFIKIETWHKPDLGTLENVHGLD 129

  Fly   130 GSDLRNRIVDVIDIV-KDQLWGGDYVKEEDPKHFVSDKTGRGPLAEDWLEEYWREVKGKKQPTPR 193
            .:..:...:..|||. :.|:...||..:|||..|.|.||.||||..:|.:|.        ..||
  Rat   130 PNTWKTVEIVHIDIADRSQVEPADYKADEDPALFQSVKTKRGPLGPNWKKEL--------ANTP- 185

  Fly   194 NMSLMTAYKICRVEFRYWGMQTKLEKFIHDVALRKMMLRAHRQAWAWQDEWFGLTIEDIRELERQ 258
            :...|.|||:..::|::||:|:|:|.||.... :::....|||.:.|.|:|..||:||||.:|.:
  Rat   186 DCPKMCAYKLVTIKFKWWGLQSKVENFIQKQE-KRIFTNLHRQLFCWIDKWIDLTMEDIRRMEDE 249

  Fly   259 TQLAL------AKKMGGGEECSD 275
            ||..|      .:..|....|.|
  Rat   250 TQKELETLRSQGQVRGTSAACDD 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgB	NP_001259535.1	SRPBCC_PITPNM1-2_like	1..268	CDD:176898	106/274 (39%)
		DDHD	746..924	CDD:280937
		LNS2	1072..1203	CDD:197870
Pitpnb	XP_006249584.1	SRPBCC_PITPNA-B_like	3..258	CDD:176897	106/266 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5083
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810