Protein Alignment rdgB and pitpnm2

DIOPT Version :9

• Sequence 1: NP_001259535.1
• Gene: rdgB / 32340
• FlyBaseID: FBgn0003218
• Length: 1297
• Species: Drosophila melanogaster
• Sequence 2: XP_017209902.1
• Gene: pitpnm2 / 100333901
• -ID: -
• Length: 1338
• Species: Danio rerio
• Alignment Length: 1410
• Identity: 620/1410 - (43%)
• Similarity: 834/1410 - (59%)
• Gaps: 263/1410 - (18%)

  Fly     1 MLIKEYRIPLPLTVEEYRIAQLYMIAKKSREESHGEGSGVEIIINEPYKDGPGGNGQYTKKIYHV 65
            |||||||||:||:||||||||||||.|||||||.||||||||:.|.||.|||||:||||:|:||:
Zfish     1 MLIKEYRIPMPLSVEEYRIAQLYMIQKKSREESEGEGSGVEILENRPYTDGPGGSGQYTRKVYHI 65

  Fly    66 GNHLPGWIKSLLPKSALTVEEEAWNAYPYTRTRYTCPFVEKFSLDIETYYYPDNGYQDNVFQLSG 130
            |.|:|.|.:|:|||:||.||||:||||||||||:|||||||||:||||||.||.|.|::||.||.
Zfish    66 GQHIPSWFRSILPKAALRVEEESWNAYPYTRTRHTCPFVEKFSIDIETYYKPDTGSQNDVFNLSS 130

  Fly   131 SDLRNRIVDVIDIVKDQLWGGDYVKEEDPKHFVSDKTGRGPLAEDWLEEYWREVKGKKQPTPRNM 195
            ::.|.|.:|.||||||.:...:|:.|||||.:.|:||.||||::||:    .|:......||
Zfish   131 AEKRQRDIDPIDIVKDFIAPHEYLVEEDPKLYKSNKTQRGPLSDDWI----TEINNNPGKTP--- 188

  Fly   196 SLMTAYKICRVEFRYWGMQTKLEKFIHDVALRKMMLRAHRQAWAWQDEWFGLTIEDIRELERQTQ 260
             :|.|||:|:|||||||||:|:|:|||||.|||:|:|||||||.|||||:|||:||||:||.:||
Zfish   189 -VMCAYKLCKVEFRYWGMQSKIERFIHDVGLRKVMVRAHRQAWCWQDEWYGLTMEDIRQLELETQ 252

  Fly   261 LALAKKM--------GGGEECSDDSVSEPYVSTAATAASTTGSERKKSAPAVPPIVTQQPPSAEA 317
            ||||:||        |||..|                    |.:::...||
Zfish   253 LALAQKMAQYSEEAEGGGAPC--------------------GQQKESEEPA-------------- 283

  Fly   318 SSDEEGEEEEDDDEDENDAIGTGVDLSANQGGSAQRSRSQSIQMAQKGKFGSKGALHSPVGSAHS 382
              :..|...|.|.|             |..||...::|.   ::.::....|:.:..|..|.
Zfish   284 --ESRGSRVEADGE-------------ARSGGDTLQARG---ELTKQWSTSSRSSRSSKRGG--- 327

  Fly   383 FDLQSKKPHAKTAPRRH-VANWRMERLEVDSKSNSDEEFFDC---LDTNE---TNSLAKWSSLEL 440
                        :|.|| ::.|||:.:..||:.::|:||||.   ...||   ...:.||||.:|
Zfish   328 ------------SPSRHSISEWRMQSIARDSEDSTDDEFFDAHEDFSDNEEIFAKEITKWSSNDL 380

  Fly   441 LGEGDDSPPPHGGPSSAASVGGRGNSRQEDSIFNQDFLMRVASERGNKRQLRSSASVDRSHD--S 503
            :.:.:.:               .....|||          :..|.|.  :...:..|:|.|:  |
Zfish   381 MDKIETA---------------EAEEAQED----------LFQESGG--EFSGTTGVERLHEECS 418

  Fly   504 SPPGSPSTPSCPTTILILVVHAGSVLDAAS-ELTAKKSDVTTFRGSFEAVMRQHYPSLLTHVTIK 567
            |..|..|:   ...:|:||:|.|::||:.| :.::|::||.|...:||||||.|:||.|..:.|:
Zfish   419 SQQGLQSS---KLHVLLLVLHGGNILDSGSADQSSKQADVHTLSAAFEAVMRLHFPSALGRIAIR 480

  Fly   568 MVPCPSICTDALGILSSLSPYSFDAS--PSAADIPNIADVPIGAIPLLSVASPEFHETVNKTVAA 630
            :||||::|.:|..::|:|||||:|..  .|:.|     .:|:.|:|||:.::|::.:.|...:..
Zfish   481 LVPCPAVCVEAFSLVSNLSPYSYDEGCLSSSQD-----HIPLAALPLLATSAPQYQDAVATVIIR 540

  Fly   631 ANIVYHEFLKSEEGHGFSGQIVMLGDSMGSLLAYEALCRSN------------GS---------- 673
            ||.||.:||:|.:|..|:||:.::||.:|.:|.::|||.||            ||
Zfish   541 ANQVYGDFLRSLDGASFTGQVCLIGDCVGGILGFDALCSSNVTVSESQNSSRRGSIISVQDSELL 605

  Fly   674 QPGTASGASNSGG--DAATNINTHNPLS------PRNSRLDDDERFIEADLDAKR---------- 720
            .||.....|.|||  ::|.::.....||      ||.|..|:.::    .|..||
Zfish   606 SPGIIINCSGSGGSSNSALSLEGSRHLSRSNIDIPRCSAADEHKK----QLPRKRSDSSTYEIDT 666

  Fly   721 -------------LLVAPSPRRRRSSSSS----DSRATKLDFEVCDFFMFGSPLSVVLAARKLHD 768
                         .::...|..||||||:    .....|.||||.|||:|||||.:|||.|
Zfish   667 IKQHQAFLSSLHSSVLRTDPASRRSSSSTMLEGGGALGKFDFEVSDFFLFGSPLGLVLALR---- 727

  Fly   769 AKAALP-------RPNCHQVYNLFHPTDPIASRLEPLLSARFSILAPVNVPRYAKYPLGNGQPLH 826
             |..:|       ||.|.||||||||.||.||||||||..||.::.|.:||||.::|||:||...
Zfish   728 -KTVVPTLDVCHLRPACQQVYNLFHPADPSASRLEPLLEKRFHLMPPFSVPRYQRFPLGDGQSAL 791

  Fly   827 LLEVIQSHP---------------------------------------------QH---FNDGNN 843
            |:|.:||:|                                             .|   |::.:|
Zfish   792 LVETVQSNPHLLLESVSCAAQRCPDGVSETSIPVPVLNWQNSAPATAAETDVMQSHGLMFSEHSN 856

  Fly   844 ---------LLAGRRLSDASMQSTISGLIENVSLSTIHALQNKWWGTKRLDYALYCPEGLSNFPA 899
                     ....||.|:.|:.|.:|||.::.:.|.|..:.::||||||:|:|||||:.|:.||.
Zfish   857 PSSPAAIPAFRGARRASETSIASQVSGLADSYTASNIANIASRWWGTKRVDFALYCPDALTAFPT 921

  Fly   900 HALPHLFHASYWESPDVIAFILRQIGKFEGIPFVGSNDDKDNASFHPGQPREKWIKKRTSVKLKN 964
            .|||||||||||||.||::|:|||:.:.|....: ..|.|:.:.|.|.:||||||:|||.||::|
Zfish   922 VALPHLFHASYWESTDVVSFLLRQVMRHENSSIL-ELDGKEVSEFTPSKPREKWIRKRTHVKIRN 985

  Fly   965 VAANHRANDVIVQEGREQRLNARFMYGPLDMITLHGEKVDVHIMKDPPAGEWTFLSTEVTDKNGR 1029
            |.||||.||.:..|...|.:..|||||||||:||.|||||||||..||:|||.:.|||:|:.:||
Zfish   986 VTANHRVNDAVFTEDGNQVVTGRFMYGPLDMVTLTGEKVDVHIMTQPPSGEWVYFSTELTNSSGR 1050

  Fly  1030 ISYSIPDQVSLGYGIYPVKMVVRGDHTSVDCYMAVVPPLTECVVFSIDGSFTASMSVTGRDPKVR 1094
            :.|.|||...|..|:|||||||||||||.|.|:.|:|..||.|||||||||.||:|:.|.|||||
Zfish  1051 VFYEIPDSKRLSIGVYPVKMVVRGDHTSADSYLTVLPRGTEFVVFSIDGSFAASVSIMGSDPKVR 1115

  Fly  1095 AGAVDVCRHWQELGYLLIYITGRPDMQQQRVVSWLSQHNFPHGLISFADGLSTDPLGHKTAYLNN 1159
            ||||||.||||:||||::|:|||||||:||||:||||||||||::||.|||..|||.||..:|..
Zfish  1116 AGAVDVVRHWQDLGYLIVYVTGRPDMQKQRVVAWLSQHNFPHGIVSFCDGLVHDPLRHKANFLKT 1180

  Fly  1160 LVQNHGISITAAYGSSKDISVYTNVGMRTDQIFIVGKVGKKLQSNATVLSDGYAAHLAGLQAVGG 1224
            ||....:.|.|||||:|||||||::|:...||:|||:..||:|.....::||||:||:.|:....
Zfish  1181 LVTEAHMKIFAAYGSTKDISVYTSLGLPPAQIYIVGRPTKKMQHQCQFITDGYASHLSQLEYNQR 1245

  Fly  1225 SRPAK-GNARMVIPRGCFNLPGQTANPRRRSNAFELQLANISPSS 1268
            ||||| |:.|||:.:|.|.| |.....|:|::......:..||::
Zfish  1246 SRPAKTGSTRMVLRKGSFGL-GSGDFLRKRNHLLRTISSQPSPTT 1289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdgB	NP_001259535.1	SRPBCC_PITPNM1-2_like	1..268	CDD:176898	181/274 (66%)
		DDHD	746..924	CDD:280937	100/241 (41%)
		LNS2	1072..1203	CDD:197870	88/130 (68%)
pitpnm2	XP_017209902.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	379	1.000	Domainoid score	I810
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7915
Inparanoid	1	1.050	782	1.000	Inparanoid score	I503
OMA	1	1.010	-	-		QHG48872
OrthoDB	1	1.010	-	-		D122895at2759
OrthoFinder	1	1.000	-	-		FOG0002342
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104036
Panther	1	1.100	-	-	LDO	PTHR10658
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1383
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.980