Protein Alignment HOXD8 and unpg

DIOPT Version :10

• Sequence 1: NP_062458.1
• Gene: HOXD8 / 3234
• HGNCID: 5139
• Length: 290
• Species: Homo sapiens
• Sequence 2: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Alignment Length: 287
• Identity: 74/287 - (25%)
• Similarity: 94/287 - (32%)
• Gaps: 110/287 - (38%)

Human    56 NSAAGFPHA-PPQAHAHPHPSPP---------------------------PSGTGCGG------- 85
            :|.||.|.| .|||.|.|.|.||                           |:..|...
  Fly   112 SSPAGHPAAQQPQAQAQPQPPPPHPPTHALEKQLPPTLPHPLDTRFLPFNPAAAGVAPTDLSYRR 176

Human    86 -REGRGQEYFH-----------------------PGGGSPAAAYQAAPPPPPHPPP-------PP 119
             .|...|:|.|                       ||    .|..|...||..|..|       |.
  Fly   177 LAELMNQDYVHSLSVHARLQHMAAAGRMHEDQANPG----MAQLQEPTPPQAHSSPAKSGSHSPM 237

Human   120 PPP---------PCGGIACHG-----EPAKFYGYDNLQRQPIFTTQQEAELVQYPDC-------- 162
            .|.         .|.|.:|..     .|..:.|..:..|...:|....      .||
  Fly   238 EPALDVGMDEDFECSGDSCSDISLTMSPRNYNGEMDKSRNGAYTNSDS------EDCSDDEGAQS 296

Human   163 KSSSGNIGEDPDHLNQSSSPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRR 227
            :...|.:|......|.|||.|:            .||.|..::..|.||||:||....||:...|
  Fly   297 RHEGGGMGGKDSQGNGSSSNSK------------SRRRRTAFTSEQLLELEREFHAKKYLSLTER 349

Human   228 IEVSHALALTERQVKIWFQNRRMKWKK 254
            .:::.:|.|:|.||||||||||.|||:
  Fly   350 SQIATSLKLSEVQVKIWFQNRRAKWKR 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXD8	NP_062458.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	60..127		28/141 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	161..200		10/46 (22%)
		Homeodomain	198..254	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	255..290		74/287 (26%)
unpg	NP_477146.1	Homeodomain	324..376	CDD:459649	25/51 (49%)