DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Yp3 and Pnlip

DIOPT Version :9

Sequence 1:	NP_001285228.1	Gene:	Yp3 / 32339	FlyBaseID:	FBgn0004047	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_081201.2	Gene:	Pnlip / 69060	MGIID:	97722	Length:	465	Species:	Mus musculus

Alignment Length:	273	Identity:	76/273 - (27%)
Similarity:	118/273 - (43%)	Gaps:	60/273 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 LTGLPKTSPAQQKAMRRLIQAYVQKYNLQQLQKNAQEQQQQLKSSDYDYTSS---------EEAA 182
            |..|| .||||... |.|:.......|.|.:..:|    ..:::|::.....         ::..
Mouse    41 LKALP-WSPAQINT-RFLLYTNENPDNYQLITSDA----SNIRNSNFRTNRKTRIIIHGFIDKGE 99

  Fly   183 DQWKS------AKAASGDLIIID-LGSTLTNFKRYAMLDVLNTGAMIGQTLIDL--TNKGVPQEI 238
            :.|.|      .:..|.:.|.:| .|.:.|.:.: |..:|...||.:. .|:::  ::.|.....
Mouse   100 ENWLSDMCKNMFRVESVNCICVDWKGGSRTTYTQ-ATQNVRVVGAEVA-LLVNVLQSDLGYSLNN 162

  Fly   239 IHLIGQGISAHVAGAAGNKYTAQTGHKLRRITGLDPAKVLSKRPQILG-----GLSRGDADFVDA 298
            :||||..:.:|:||.||.:.....|    ||||||||:     |...|     .|...||.||||
Mouse   163 VHLIGHSLGSHIAGEAGKRTFGAIG----RITGLDPAE-----PYFQGTPEEVRLDPTDAQFVDA 218

  Fly   299 IHTST--------FAMGTPIRCGDVDFYPNGPSTGVPG-SENVIEAVARATRYFAESVRPGSERN 354
            |||..        |.|...:  |.:||:||| ...:|| .:|::..:..     .:.:..|: ||
Mouse   219 IHTDAGPIIPNLGFGMSQTV--GHLDFFPNG-GIEMPGCQKNILSQIVD-----IDGIWEGT-RN 274

  Fly   355 FPAVPANSLKQYK 367
            |.|  .|.|:.||
Mouse   275 FAA--CNHLRSYK 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Yp3	NP_001285228.1	Lipase	93..400	CDD:278576	76/273 (28%)
Yp3	NP_001285228.1	Abhydrolase	<215..396	CDD:304388	55/169 (33%)
Pnlip	NP_081201.2	Lipase	18..352	CDD:278576	76/273 (28%)
		Pancreat_lipase_like	51..348	CDD:238363	69/262 (26%)
		PLAT_PL	355..465	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835303
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840