DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Yp3 and PNLIPRP1

DIOPT Version :9

Sequence 1:	NP_001285228.1	Gene:	Yp3 / 32339	FlyBaseID:	FBgn0004047	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_001290064.1	Gene:	PNLIPRP1 / 5407	HGNCID:	9156	Length:	467	Species:	Homo sapiens

Alignment Length:	215	Identity:	67/215 - (31%)
Similarity:	89/215 - (41%)	Gaps:	51/215 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 WKSAKAASGDLIIIDLGSTLTNFKRYAMLDVLNTGAMIGQTL-IDLTNKGVPQEIIHLIGQGISA 248
            ||....|           |.|.    |..:|...||.:.|.| |.||....|...:||||..:.|
Human   125 WKKGSQA-----------TYTQ----AANNVRVVGAQVAQMLDILLTEYSYPPSKVHLIGHSLGA 174

  Fly   249 HVAGAAGNKYTAQTGHKLRRITGLDPAKV-LSKRPQILGGLSRGDADFVDAIHTST------FAM 306
            ||||.||:|...     |.|||||||.:. ....|:.: .|...||||||.|||..      ...
Human   175 HVAGEAGSKTPG-----LSRITGLDPVEASFESTPEEV-RLDPSDADFVDVIHTDAAPLIPFLGF 233

  Fly   307 GTPIRCGDVDFYPNGPSTGVPG-SENVIEAVA------------------RATRYFAESVRPGSE 352
            ||..:.|.:||:||| ...:|| .:|.:..:.                  |:.:|:.||:.  :.
Human   234 GTNQQMGHLDFFPNG-GESMPGCKKNALSQIVDLDGIWAGTRDFVACNHLRSYKYYLESIL--NP 295

  Fly   353 RNFPAVPANSLKQYKEQDGF 372
            ..|.|.|..|.|.::....|
Human   296 DGFAAYPCTSYKSFESDKCF 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Yp3	NP_001285228.1	Lipase	93..400	CDD:278576	67/215 (31%)
Yp3	NP_001285228.1	Abhydrolase	<215..396	CDD:304388	61/185 (33%)
PNLIPRP1	NP_001290064.1	Lipase	18..353	CDD:278576	67/215 (31%)
		Pancreat_lipase_like	52..349	CDD:238363	67/215 (31%)
		PLAT_PL	356..467	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145202
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840