DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Yp3 and lipca

DIOPT Version :9

Sequence 1:	NP_001285228.1	Gene:	Yp3 / 32339	FlyBaseID:	FBgn0004047	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_957316.1	Gene:	lipca / 393997	ZFINID:	ZDB-GENE-040426-1361	Length:	514	Species:	Danio rerio

Alignment Length:	199	Identity:	60/199 - (30%)
Similarity:	92/199 - (46%)	Gaps:	37/199 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 DQW-----KSAKAASGDLIIIDLGSTLTNFKRYAMLDVLNTGAMIGQTLIDLTN-----KGVPQE 237
            ::|     .:.|::.|::.:: :...||...::..:...|| .::||.:..|.:     |..|..
Zfish    94 EKWISRLASALKSSEGNINVL-IADWLTLAHQHYPIAAQNT-RIVGQDIAHLLSWLEDFKQFPLG 156

  Fly   238 IIHLIGQGISAHVAGAAGNKYTAQTGHKLRRITGLDPAKVLSKRPQILGGLSRGDADFVDAIHTS 302
            .:||||..:.||::|.||:. .|.:|..|.||||||||..:.:.......||..||.|||||||.
Zfish   157 KVHLIGYSLGAHISGFAGSN-LAMSGRTLGRITGLDPAGPMFEGMSHTDRLSPEDAKFVDAIHTF 220

  Fly   303 T-----FAMGTPIRCGDVDFYPNGPS------------------TGVPGSENVIE-AVARATRYF 343
            |     .::|........||||||.|                  .|:.|.|..:: |..||...|
Zfish   221 TLQRMGLSVGIKQPVAHFDFYPNGGSFQPGCQLHMQNIYAHLAQHGIMGFEQTVKCAHERAVHLF 285

  Fly   344 AESV 347
            .:|:
Zfish   286 IDSL 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Yp3	NP_001285228.1	Lipase	93..400	CDD:278576	60/199 (30%)
Yp3	NP_001285228.1	Abhydrolase	<215..396	CDD:304388	55/162 (34%)
lipca	NP_957316.1	lipo_lipase	44..488	CDD:132274	60/199 (30%)
		Pancreat_lipase_like	54..344	CDD:238363	60/199 (30%)
		PLAT_LPL	351..485	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910