DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Yp3 and Yp2

DIOPT Version :9

Sequence 1:	NP_001285228.1	Gene:	Yp3 / 32339	FlyBaseID:	FBgn0004047	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_001285070.1	Gene:	Yp2 / 31938	FlyBaseID:	FBgn0005391	Length:	442	Species:	Drosophila melanogaster

Alignment Length:	430	Identity:	215/430 - (50%)
Similarity:	295/430 - (68%)	Gaps:	17/430 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MMSLR-ICLLATCLLVAAHASKDASN---------DRL-KPTKWLTATELENVPSLNDITWERLE 54
            |..|| :|::| |||..|..:..:.|         |.: :|:.|:...|:|.:|:|.::|.::|:
  Fly     1 MNPLRTLCVMA-CLLAVAMGNPQSGNRSGRRSNSLDNVEQPSNWVNPREVEELPNLKEVTLKKLQ 64

  Fly    55 NQPLEQGAKVIEKIYHVGQIKHDLTPSFVPSPSNVPVWIIKSNGQKVECKLNNYVETAKAQPGFG 119
            ...||:||.:::|:||:.|..|...|.:.|.||.:..:|:...|||:|..||..||..|.|..||
  Fly    65 EMSLEEGATLLDKLYHLSQFNHVFKPDYTPEPSQIRGYIVGERGQKIEFNLNTLVEKVKRQQKFG 129

  Fly   120 EDEVTIVLTGLPKTSPAQQKAMRRLIQAYVQKYNLQQLQKN--AQEQQQQLKSSDYDYTSSEEAA 182
            :|||||.:.|||:|:...|||.|:|:|||.|:||||..:..  :.|:|.|..||:...|...:..
  Fly   130 DDEVTIFIQGLPETNTQVQKATRKLVQAYQQRYNLQPYETTDYSNEEQSQRSSSEEQQTQRRKQN 194

  Fly   183 DQWKSAKAASGDLIIIDLGSTLTNFKRYAMLDVLNTGAMIGQTLIDLTNK-GVPQEIIHLIGQGI 246
            .:....|  :||||:|.||:.:.:|::||.|::...|.:||..|::|||. .||||||||||.|.
  Fly   195 GEQDDTK--TGDLIVIQLGNAIEDFEQYATLNIERLGEIIGNRLVELTNTVNVPQEIIHLIGSGP 257

  Fly   247 SAHVAGAAGNKYTAQTGHKLRRITGLDPAKVLSKRPQILGGLSRGDADFVDAIHTSTFAMGTPIR 311
            :|||||.||.::|.||||||||||.|||.|:..|..:.|.||:|||||||||||||.:.|||..|
  Fly   258 AAHVAGVAGRQFTRQTGHKLRRITALDPTKIYGKPEERLTGLARGDADFVDAIHTSAYGMGTSQR 322

  Fly   312 CGDVDFYPNGPSTGVPGSENVIEAVARATRYFAESVRPGSERNFPAVPANSLKQYKEQDGFGKRA 376
            ..:|||:||||||||||::||:||..|||||||||||||:|||||:|.|:|.::||:..|:|||.
  Fly   323 LANVDFFPNGPSTGVPGADNVVEATMRATRYFAESVRPGNERNFPSVAASSYQEYKQNKGYGKRG 387

  Fly   377 YMGLQIDYDLRGDYILEVNAKSPFGQRSPAHKQAAYHGMH 416
            |||:..|:||:|||||:||:|||||:.:||.||..||.:|
  Fly   388 YMGIATDFDLQGDYILQVNSKSPFGRSTPAQKQTGYHQVH 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Yp3	NP_001285228.1	Lipase	93..400	CDD:278576	173/309 (56%)
Yp3	NP_001285228.1	Abhydrolase	<215..396	CDD:304388	117/181 (65%)
Yp2	NP_001285070.1	Lipase	97..411	CDD:278576	174/315 (55%)
Yp2	NP_001285070.1	Abhydrolase	<221..407	CDD:304388	119/185 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438287
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007604
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840