DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Yp3 and Lipc

DIOPT Version :9

Sequence 1:	NP_001285228.1	Gene:	Yp3 / 32339	FlyBaseID:	FBgn0004047	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	XP_006510879.1	Gene:	Lipc / 15450	MGIID:	96216	Length:	526	Species:	Mus musculus

Alignment Length:	278	Identity:	71/278 - (25%)
Similarity:	116/278 - (41%)	Gaps:	58/278 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   169 KSSDYDYTSSEEAADQW-----KSAKAASGDLIIIDLGSTLTNFKRYAMLDVLNTGAMIGQTLID 228
            |.||.|| ..:...:.|     .:.|:.....:.:.|...::...::..:.|.|| .::||.:..
Mouse   101 KDSDSDY-QVDGLLENWIWKIVSALKSRQSQPVNVGLVDWISLAYQHYTIAVQNT-RIVGQDVAA 163

  Fly   229 L-----TNKGVPQEIIHLIGQGISAHVAGAAGNKYTAQTGHKLRRITGLDPAKVLSKRPQILGGL 288
            |     .:....:..:||||..:.|||:|.||:....:  :|:.||||||||..:.:.......|
Mouse   164 LLLWLEESAKFSRSKVHLIGYSLGAHVSGFAGSSMDGK--NKIGRITGLDPAGPMFEGTSPNERL 226

  Fly   289 SRGDADFVDAIHTST-----FAMGTPIRCGDVDFYPNGPSTGVPG----------SENVIEAVA- 337
            |..||:|||||||.|     .::|........||||||.|. .||          :|:.:.|:.
Mouse   227 SPDDANFVDAIHTFTREHMGLSVGIKQPIAHYDFYPNGGSF-QPGCHFLELYKHIAEHGLNAITQ 290

  Fly   338 -------RATRYFAESVRPGSERNFPAVPANSLKQYKEQDGFGKRAYMGLQ------IDYDLRGD 389
                   |:...|.:|::....::...       |..:...|.:...:..:      :.||:|.|
Mouse   291 TIKCAHERSVHLFIDSLQHSDLQSIGF-------QCSDMGSFSQGLCLSCKKGRCNTLGYDIRKD 348

  Fly   390 -------YILEVNAKSPF 400
                   ..|...|:|||
Mouse   349 RSGKSKRLFLITRAQSPF 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Yp3	NP_001285228.1	Lipase	93..400	CDD:278576	69/276 (25%)
Yp3	NP_001285228.1	Abhydrolase	<215..396	CDD:304388	59/221 (27%)
Lipc	XP_006510879.1	Lipase	18..366	CDD:333880	69/276 (25%)
Lipc	XP_006510879.1	PLAT_LPL	369..504	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910