DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Yp3 and Pnliprp2

DIOPT Version :9

Sequence 1:	NP_001285228.1	Gene:	Yp3 / 32339	FlyBaseID:	FBgn0004047	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_476554.1	Gene:	Pnliprp2 / 117554	RGDID:	620793	Length:	482	Species:	Rattus norvegicus

Alignment Length:	363	Identity:	82/363 - (22%)
Similarity:	134/363 - (36%)	Gaps:	112/363 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 NDITWERLENQPLEQGAKVIEKIYHVGQIKHDLTPSFVPSPSNVPV-WIIKSNGQKVECKLNNYV 109
            ||..|..:..:||        ||             |..||.::.. :::.:|...     |||.
  Rat    43 NDKPWAGMLQRPL--------KI-------------FPWSPEDIDTRFLLYTNENP-----NNYQ 81

  Fly   110 ETAKAQPGFGEDEVTIVLTGLPKTSPAQ-QKAMRRLIQAYVQK----YNLQQLQKNAQEQQQQLK 169
            :.:..:|.      ||      |.|..| .:..|.::..::.|    :.|...:|..|.::....
  Rat    82 KISATEPD------TI------KFSNFQLDRKTRFIVHGFIDKGEDGWLLDMCKKMFQVEKVNCI 134

  Fly   170 SSDYDYTSSEEAADQWKSAKAASGDLIIIDLGSTLTNFKRYAMLDVLNTGAMIGQTLIDLTNKGV 234
            ..|:...|..|......:.:....::..              ::.||:            |..|.
  Rat   135 CVDWRRGSRTEYTQASYNTRVVGAEIAF--------------LVQVLS------------TEMGY 173

  Fly   235 PQEIIHLIGQGISAHVAGAAGNKYTAQTGHKLRRITGLDPAKVLSKRPQILG-----GLSRGDAD 294
            ..|.:||||..:.|||.|.||.:.....|    ||||||||:     |...|     .|...||.
  Rat   174 SPENVHLIGHSLGAHVVGEAGRRLEGHVG----RITGLDPAE-----PCFQGLPEEVRLDPSDAM 229

  Fly   295 FVDAIHTST------FAMGTPIRCGDVDFYPNGPSTGVPG-SENVIEAVA--------------- 337
            |||.|||.:      ...|...:.|.:||:||| ...:|| .:|::..:.
  Rat   230 FVDVIHTDSAPIIPYLGFGMSQKVGHLDFFPNG-GKEMPGCQKNILSTIVDINGIWEGTQNFVAC 293

  Fly   338 ---RATRYFAESVRPGSERNFPAVPANSLKQYKEQDGF 372
               |:.:|:|.|:.  :...|...|.:|.:::::.|.|
  Rat   294 NHLRSYKYYASSIL--NPDGFLGYPCSSYEKFQQNDCF 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Yp3	NP_001285228.1	Lipase	93..400	CDD:278576	72/315 (23%)
Yp3	NP_001285228.1	Abhydrolase	<215..396	CDD:304388	54/188 (29%)
Pnliprp2	NP_476554.1	Lipase	31..367	CDD:278576	82/363 (23%)
		Pancreat_lipase_like	65..363	CDD:238363	72/320 (23%)
		PLAT_PL	370..482	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910