Protein Alignment Rtc1 and RTCA

DIOPT Version :9

• Sequence 1: NP_572919.1
• Gene: Rtc1 / 32338
• FlyBaseID: FBgn0020909
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_001124313.1
• Gene: RTCA / 8634
• HGNCID: 17981
• Length: 379
• Species: Homo sapiens
• Alignment Length: 399
• Identity: 104/399 - (26%)
• Similarity: 173/399 - (43%)
• Gaps: 44/399 - (11%)

  Fly     2 PPIAQEGNCLIYRGSNFLKQRLILACLSGKPVKISQIRSEDETAPGL-------------REYEI 53
            |.:..:|: ::..|...|:....|:||.|.|:::.:||:...| |||             |...:
Human     4 PRVEVDGS-IMEGGGQILRVSTALSCLLGLPLRVQKIRAGRST-PGLSSGGWKSKIKVLTRPQHL 66

  Fly    54 SLIRLLDKITNGTKIELNPAGTSVMFSPGLLHGGQLNHDCCVQRGIGYYLDALIALGPFCKSPLQ 118
            |.:.::..:.:|.........|.:.|:|..:.||....|......:...:...:....|..||.:
Human    67 SGLEMIRDLCDGQLEGAEIGSTEITFTPEKIKGGIHTADTKTAGSVCLLMQVSMPCVLFAASPSE 131

  Fly   119 CTLRGVTNSKDSPSVDHIKGAALSLLKRFLLVDEGLELKVVRRGVAPLGGGEIIFRCPVRKSLRA 183
            ..|:|.||::.:|.:|:.......::::|..:   ....:..||..|.||||:|.|....|.|..
Human   132 LHLKGGTNAEMAPQIDYTVMVFKPIVEKFGFI---FNCDIKTRGYYPKGGGEVIVRMSPVKQLNP 193

  Fly   184 IQFQSQGMVKRIRGTVYACKVSP-AMANRTVEAAKGCMLKFLPDVYIY---TDQNKGKMSGNSPG 244
            |....:|.|.:|.|..:...|.| .:|.....||..|:.|.:.|:|:.   ..:.|.:..||  |
Human   194 INLTERGCVTKIYGRAFVAGVLPFKVAKDMAAAAVRCIRKEIRDLYVNIQPVQEPKDQAFGN--G 256

  Fly   245 FGICLIAETTDGVCFAADCCSNTREESEDTPSIPENLGKEVALRLLDEIYRGGCVDSSYQWLAAL 309
            .||.:||||:.|..||..........:       :.:|.|.|..||..:..||.||...|....:
Human   257 NGIIIIAETSTGCLFAGSSLGKRGVNA-------DKVGIEAAEMLLANLRHGGTVDEYLQDQLIV 314

  Fly   310 YIALGQKHVSKFLTGALSNYT---VHFLQHLRDFFSITFKLENPEAEDEDEAENVRGAQKVLMAC 371
            ::||. ..||:..||.::.:|   :||.:.:.....|..|     :|||::|    .....::.|
Human   315 FMALA-NGVSRIKTGPVTLHTQTAIHFAEQIAKAKFIVKK-----SEDEEDA----AKDTYIIEC 369

  Fly   372 VGIGYTNIN 380
            .|||.||.|
Human   370 QGIGMTNPN 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rtc1	NP_572919.1	RNA_Cyclase_Class_I	7..349	CDD:238447	92/361 (25%)
		18S_RNA_Rcl1p	11..384	CDD:274564	102/390 (26%)
RTCA	NP_001124313.1	RNA_3prim_cycl	6..350	CDD:274563	90/358 (25%)
		RNA_Cyclase_Class_II	8..353	CDD:238446	91/359 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0430
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810