DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pdcd4 and AT1G22730

DIOPT Version :9

Sequence 1:	NP_001096977.1	Gene:	Pdcd4 / 32337	FlyBaseID:	FBgn0030520	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_173687.1	Gene:	AT1G22730 / 838879	AraportID:	AT1G22730	Length:	693	Species:	Arabidopsis thaliana

Alignment Length:	391	Identity:	116/391 - (29%)
Similarity:	180/391 - (46%)	Gaps:	70/391 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 GGKGVWGLPGSEALAEVYEDENDPNYDSE---CNDRNVELREVITEITREEFFKLAEPIVLEYYE 210
            |.:..||:...:.|.:...|..:.|..|:   |.|.::           .|:.|.|..||.||:.
plant    51 GSEETWGVEDDDDLTDPIFDTIEGNGHSDPTSCFDADL-----------SEYKKKATVIVEEYFG 104

  Fly   211 HGDPHEVALSFDEILQAPMREHVTSILVEIAMDHKDSQREMTSVLISDLYGRVITGKDIEKGFNM 275
            ..|...|.....|:..|..|.:....||.:|||..|.::||.:.|:|.||..||...::.:|||.
plant   105 TNDVVSVVNELKELGMAEYRYYFVKKLVSMAMDRHDKEKEMAAFLLSTLYADVIDPPEVYRGFNK 169

  Fly   276 LLANLPDLVLDTPEAPIMLGNFMARAVADDCIPPKFV----------AKSGEELR-----HLGLG 325
            |:|:..||.:|.|:|..:|..|:|||:.||.:||.|:          :|..|.||     :|...
plant   170 LVASADDLSVDIPDAVDVLAVFVARAIVDDILPPAFLKKQMKLLPDNSKGVEVLRKAEKSYLATP 234

  Fly   326 EHAEQALRRADSLIYKHVWAHLDNVWGMGGPLRPVKTITMQMELLLKEYLSSRDVAEAQRCLRAL 390
            .|||...:|         |...|| |       ..:.:..::..|||||:.|.|..||.||::.|
plant   235 LHAEVVEKR---------WGGTDN-W-------TAEDVKARINDLLKEYVMSGDKKEAFRCIKGL 282

  Fly   391 EVPHYHHELVYEAIVMTLESLSQTTEEAMCELLKQLDLTCLVLPAGMEQGFLRAFDDMADIVLDV 455
            :||.:|||:|..|::|.:|  .:..:..:.:|||:.....|:....:.:||.|..|.:.|:.||:
plant   283 KVPFFHHEIVKRALIMAME--RRKAQVRLLDLLKETIEVGLINSTQVTKGFSRIIDSIEDLSLDI 345

  Fly   456 PLAYIILDRFVERCNRAGFLT------------DKIINN---------VPSRGRKRFVSEGDGGH 499
            |.|..||..|:.:....|:|.            :|::.|         ..|..|:.|:| ||...
plant   346 PDARRILQSFISKAASEGWLCASSLKSLSADAGEKLLENSSANVFKDKAKSIIREYFLS-GDTSE 409

  Fly   500 V 500
            |
plant   410 V 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pdcd4	NP_001096977.1	MA3	197..308	CDD:214714	42/110 (38%)
Pdcd4	NP_001096977.1	MA3	363..476	CDD:280933	38/112 (34%)
AT1G22730	NP_173687.1	MA3	91..202	CDD:214714	42/110 (38%)
		MA3	255..366	CDD:214714	38/112 (34%)
		MA3	390..500	CDD:214714	7/22 (32%)
		MA3	561..672	CDD:367215
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	80	1.000	Domainoid score	I2986
eggNOG	1	0.900	-	-		E1_KOG0403
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D434771at2759
OrthoFinder	1	1.000	-	-		FOG0003154
OrthoInspector	1	1.000	-	-		otm2802
orthoMCL	1	0.900	-	-		OOG6_103300
Panther	1	1.100	-	-	O	PTHR12626
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2118
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.780