DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11134 and Add3

DIOPT Version :9

Sequence 1:	NP_001259530.1	Gene:	CG11134 / 32334	FlyBaseID:	FBgn0030518	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_001157571.1	Gene:	Add3 / 27360	MGIID:	1351615	Length:	706	Species:	Mus musculus

Alignment Length:	239	Identity:	49/239 - (20%)
Similarity:	80/239 - (33%)	Gaps:	84/239 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 IPSLCRQFYHLGWVTGTGGGMSI---KYNDEIYIAPSGVQKERMQPEDLFVQDITGK-------D 72
            :.||.|.....||.......:|:   |..|.|.|.|.|:.........|...:|.|:       |
Mouse   141 LASLYRLADLFGWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASTLVKVNIIGEVVDQGSTD 205

  Fly    73 LQLP--------------PEIKGLKKSQCTPLFMLAYQHRQAGAVIHTHSQHAVMATLLWPGKTF 123
            |::.              |::|                     .|||.|:    :||.  ...:.
Mouse   206 LKIDHTGFSPHAAIYSTRPDVK---------------------CVIHIHT----LATA--AVSSM 243

  Fly   124 RCTHLEMIKGVYDEADKRYLRY----DEELVVPIIENTPFERDLADSMYAAMMEYPGCSAILVRR 184
            :|..|.:.:......|..|..|    |||     .|....::.|.          |.|..:::|.
Mouse   244 KCGILPISQESLILGDVAYYDYQGSLDEE-----EERIELQKVLG----------PSCKVLVLRN 293

  Fly   185 HGVYVWGQNWEKAKTMSECYDYLFSI--AVEMK------KAGID 220
            ||:...|:      |:.|.:.|:|::  |.|::      ..|:|
Mouse   294 HGMVALGE------TLEEAFHYIFNVQMACEIQVQAVAGAGGVD 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11134	NP_001259530.1	salvage_mtnB	18..216	CDD:274521	47/233 (20%)
Add3	NP_001157571.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..23
		Aldolase_II	137..385	CDD:381867	49/239 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	471..495
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	534..556
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	574..610
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	651..706
		Interaction with calmodulin. /evidence=ECO:0000255	684..701
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0235
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810