DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11134 and Add1

DIOPT Version :9

Sequence 1:	NP_001259530.1	Gene:	CG11134 / 32334	FlyBaseID:	FBgn0030518	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_001318011.1	Gene:	Add1 / 11518	MGIID:	87918	Length:	795	Species:	Mus musculus

Alignment Length:	229	Identity:	44/229 - (19%)
Similarity:	80/229 - (34%)	Gaps:	56/229 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 FYHL----GWVTGTGGGMSIKYNDE---IYIAPSGVQKERMQPEDLFVQDITGKDLQLPPEIKGL 82
            ||.|    ||.......::.:.|.|   ..|.|.|:....:....|...::.|..:.......|:
Mouse   152 FYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSEVTASSLVKVNLQGDIVDRGSTNLGV 216

  Fly    83 KKSQCTPLFMLAYQHR-QAGAVIHTHSQHAVMATLLWPGKTFRCTHLEMIKGVYDEADKRYLRY- 145
            .::..| |....|..| .|..::|.|:......:.:      :|..|.:........|..|..|
Mouse   217 NQAGFT-LHSAVYAARPDAKCIVHIHTPAGAAVSAM------KCGLLPISPEALSLGDVAYHDYH 274

  Fly   146 ----DEELVVPIIENTPFERDLADSMYAAMMEYPGCSAILVRRHGVYVWGQNWEKAKTMSECYDY 206
                |||      |....:::|.          |....:::|.||:...|::.|      |.:.|
Mouse   275 GILVDEE------EKILIQKNLG----------PKSKVLILRNHGLVSVGESVE------EAFYY 317

  Fly   207 LFSIAV-------EMKKAG-------IDPEKFES 226
            :.::.|       .:..||       :||.|:::
Mouse   318 IHNLVVACEIQVRTLASAGGPDNLVLLDPGKYKA 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11134	NP_001259530.1	salvage_mtnB	18..216	CDD:274521	39/210 (19%)
Add1	NP_001318011.1	Aldolase_II	145..391	CDD:381867	44/229 (19%)
Add1	NP_001318011.1	PHA03307	645..>766	CDD:223039
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0235
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810