Protein Alignment Mrgn1 and mgrn1a

DIOPT Version :10

• Sequence 1: NP_572915.1
• Gene: Mrgn1 / 32330
• FlyBaseID: FBgn0030514
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: NP_001315473.2
• Gene: mgrn1a / 793939
• ZFINID: ZDB-GENE-030131-6192
• Length: 554
• Species: Danio rerio
• Alignment Length: 647
• Identity: 232/647 - (35%)
• Similarity: 327/647 - (50%)
• Gaps: 148/647 - (22%)

  Fly     1 MGNFVSRQNAAVEEADPSTNNAYKYPPRMGNFFGTHFIMGGERFDTPQPESYLFGENADLNFLGN 65
            ||:.:||:.|.||:.|...|:||:|||:.||:|.:||.||||:||||.||.||||||.|||||||
Zfish     1 MGSILSRRIAGVEDIDIQANSAYRYPPKSGNYFTSHFFMGGEKFDTPHPEGYLFGENMDLNFLGN 65

  Fly    66 RPTAFPYPPPQANEPTKTLKSLVNIRKESVRFVKTMNDKKLGGVLEKPKMKEIDRDLDLDKEKSN 130
            ||..|||..|.|:||.|||:|||||||:|:|.|:.                         |:.|:
Zfish    66 RPVQFPYVTPAAHEPVKTLRSLVNIRKDSLRLVRY-------------------------KDDSD 105

  Fly   131 VTIEDVDGNVLCSMGLGGGDADMTPPPPPCSYNIEFTFDSDAKCAITIYYFCSEDVSPSGVTLVP 195
            .|.||.            ||       |...|::||.||:||:.|||:|....|:.: :|:.:..
Zfish   106 STPEDT------------GD-------PRVLYSVEFCFDTDARVAITLYCQAFEEFA-NGMAIYS 150

  Fly   196 RE--GLTSETYHYEKGINQCFSQPSHVFNPQQMPEDELGYSPGREQYPVAIHCVVEEGSDECRQS 258
            .:  .:.|||.||::||||.||.||...:..:...:||.:...:..:|:.:..:|::|.|....:
Zfish   151 AKSPSMVSETVHYKRGINQQFSLPSFKIDFTKWKPEELNFDLDKGVFPLVVQAIVDDGDDVTGHA 215

  Fly   259 HTTICVIDHHPENGSYVLRALKQKIFVDGLCYLLQEIYGIENKAVNKT-SLDEEIDDHGSECVIC 322
            |..:...:.|.: ||:.::.||||..||.:.|||||||||||:...:| |.::|..|:.||||:|
Zfish   216 HVLLAAFERHVD-GSFSVKPLKQKQIVDRVSYLLQEIYGIENRNNQETKSTEDENSDNSSECVVC 279

  Fly   323 MSETRDTLILPCRHLCLCNSCADSLRYQANNCPICRAPFRALLQIRAVQKGI------------- 374
            :|:.|||||||||||||||:|||:||||||||||||.|||||||||||:|..
Zfish   280 LSDLRDTLILPCRHLCLCNACADTLRYQANNCPICRLPFRALLQIRAVRKKTAATLSPVSFSPVL 344

  Fly   375 ---STHVLHQNTPTSAAGEPAPVDVPPGYIPVSLIEALNGPPQYVARARNSEHDVTDSAATVAAS 436
               |.|..|.|..          ::||||.|:||:|||||
Zfish   345 SQSSDHTEHSNAD----------NIPPGYEPISLLEALNG------------------------- 374

  Fly   437 TMTSADIKATSPIKSSSQRRPKIKKNASTCTSTSEVGTITNQSG----------GGNGSS----- 486
                  ::..||...|:....:|:       .:.|:|...|.:|          .|.||.
Zfish   375 ------VQPVSPSIPSAPLYEEIQ-------FSGEMGDPLNLTGRQQNGDPGALKGKGSKSPDGS 426

  Fly   487 ----THSVEIESDPKKSSTATCTSPTLGASTSPEPKQDKLQIVNERK-YPRSTAGSGGDGSAGTD 546
                :..::.|.|.::.|..:...|......|..|.:|.::.|..:. .|.|.:.|...|.:.::
Zfish   427 VRSPSSPIQEEEDEERLSELSDAQPQSVLPCSLSPSEDTVEGVTAKPGLPNSGSESRSLGVSVSE 491

  Fly   547 --DDVDSENEKLS--------PLLSPGSKS-----KNVSSKSLKQVVACLEADDDVDNKSST 593
              .|..||...||        .|..|||..     |:.|:.|..|.:.||.:...::::..|
Zfish   492 ILQDCHSERSSLSQSESDPSADLALPGSSESIESLKSQSTNSSSQPLLCLPSSLRMEDEHLT 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mrgn1	NP_572915.1	PEX10	<255..359	CDD:227861	60/104 (58%)
		RING_Ubox	314..372	CDD:473075	48/57 (84%)
mgrn1a	NP_001315473.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	341..362		5/30 (17%)