Protein Alignment Mrgn1 and mgrn1b

DIOPT Version :10

• Sequence 1: NP_572915.1
• Gene: Mrgn1 / 32330
• FlyBaseID: FBgn0030514
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: NP_001138254.1
• Gene: mgrn1b / 553327
• ZFINID: ZDB-GENE-110401-3
• Length: 549
• Species: Danio rerio
• Alignment Length: 658
• Identity: 237/658 - (36%)
• Similarity: 329/658 - (50%)
• Gaps: 157/658 - (23%)

  Fly     1 MGNFVSRQNAAVEEADPSTNNAYKYPPRMGNFFGTHFIMGGERFDTPQPESYLFGENADLNFLGN 65
            ||:.:||:.|.||:.|...|:||:|||:.||:|.:||.||||:||||.||.||||||.|||||||
Zfish     1 MGSILSRRIAGVEDIDIQANSAYRYPPKSGNYFASHFFMGGEKFDTPHPEGYLFGENMDLNFLGN 65

  Fly    66 RPTAFPYPPPQANEPTKTLKSLVNIRKESVRFVKTMNDKKLGGVLEKPKMKEIDRDLDLDKEKSN 130
            ||..|||..|..:||.|||:|||||||:|:|.|:..:|      .:.|
Zfish    66 RPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDD------ADTP----------------- 107

  Fly   131 VTIEDVDGNVLCSMGLGGGDADMTPPPPPCSYNIEFTFDSDAKCAITIYYFCSEDVSPSGVTLVP 195
             |.|.|                    .|...|.:||||||||:.|||:|....|:.|.......|
Zfish   108 -TDEGV--------------------KPRAMYGVEFTFDSDARVAITLYCQAFEEFSNGMAIYSP 151

  Fly   196 RE-GLTSETYHYEKGINQCFSQPSHVFNPQQMPEDELGYSPGREQYPVAIHCVVEEGSDECRQSH 259
            :. .|.|||.:|::|::|.|:.||...:..:..|::|.:...|..:|:.|..||:||.|....:|
Zfish   152 KSPALVSETVYYKRGVSQQFTLPSFKIDFSEWKEEDLNFDLDRGVFPMVIQAVVDEGDDCFGHAH 216

  Fly   260 TTICVIDHHPENGSYVLRALKQKIFVDGLCYLLQEIYGIENKAVNKTS-LDEEIDDHGSECVICM 323
            ..:...:.|.: ||:.::.||||..||.:.||||||||||||...:|. .|:|..|:.:|||:|:
Zfish   217 VLLAAFERHVD-GSFSVKPLKQKQIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSNECVVCL 280

  Fly   324 SETRDTLILPCRHLCLCNSCADSLRYQANNCPICRAPFRALLQIRAVQKGISTHVLHQNTPTSAA 388
            |:.|||||||||||||||||||:||||||||||||.|||||||||||:|              ..
Zfish   281 SDLRDTLILPCRHLCLCNSCADTLRYQANNCPICRLPFRALLQIRAVRK--------------KP 331

  Fly   389 GEPAPV-------------------DVPPGYIPVSLIEALNGPPQYVARARNSEHDVTDSAATVA 434
            |..:||                   .||||:.|:||:|||||
Zfish   332 GALSPVSFSPVLAQSMDHDEHSSSDSVPPGFEPISLLEALNG----------------------- 373

  Fly   435 ASTMTSADIKATSPIKSSSQRRPKIKKNASTCTSTSEVGTITNQSGGGNGSSTHSVEIESDPKKS 499
                    :.|.||...|:....:|..:.|....:.::.: .:.||...|.       :|...||
Zfish   374 --------MGAVSPGVPSAPLYDEINFSGSLSGESRQLSS-PDHSGDSAGQ-------KSKVSKS 422

  Fly   500 STATCTSPTLGASTSPEPKQDKLQIVNERKYPR--STAGSGGDGSAGTDDDVDSENEKLSPLLSP 562
            ..:|..||   :|...|..::||..:::.:...  |::.:..:|:|| ||..||        |||
Zfish   423 PDSTLRSP---SSPIQEEDEEKLSEMSDAQAHMLLSSSPAPTEGTAG-DDAPDS--------LSP 475

  Fly   563 GSKSKNVSSKSLKQVVACLEADDDVD-NKSSTGDGPTEESSLKKGSSIKRTKPRPELSGSGAPSP 626
                               |.:|.:: ::.:..|..:|.||..|..|    :...:||..|....
Zfish   476 -------------------EEEDHLNLDEEAMNDCSSEHSSFTKTES----ETPGDLSLPGFSDS 517

  Fly   627 AEATAEDS 634
            :|:.:..|
Zfish   518 SESLSTQS 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mrgn1	NP_572915.1	PEX10	<255..359	CDD:227861	61/104 (59%)
		RING_Ubox	314..372	CDD:473075	48/57 (84%)
mgrn1b	NP_001138254.1	mRING-HC-C3HC5_RNF157	270..329	CDD:438466	48/58 (83%)