Protein Alignment Mrgn1 and Mrgn1

DIOPT Version :10

• Sequence 1: NP_572915.1
• Gene: Mrgn1 / 32330
• FlyBaseID: FBgn0030514
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: XP_061508803.1
• Gene: Mrgn1 / 1270370
• VectorBaseID: AGAMI1_010021
• Length: 860
• Species: Anopheles gambiae
• Alignment Length: 950
• Identity: 380/950 - (40%)
• Similarity: 470/950 - (49%)
• Gaps: 275/950 - (28%)

  Fly     1 MGNFVSRQNAAVEEADPSTNNAYKYPPRMGNFFGTHFIMGGERFDTPQPESYLFGENADLNFLGN 65
            ||.|.|||||.|||.|.|.|:.||||||.||:||||||||||||||||||:|||||||||||||:
Mosquito     1 MGLFASRQNATVEETDVSLNHLYKYPPRSGNYFGTHFIMGGERFDTPQPEAYLFGENADLNFLGS 65

  Fly    66 RPTAFPYPPPQANEPTKTLKSLVNIRKESVRFVKTMNDKKLGGVLEKPKMKEIDRDLDLDKEKSN 130
            :||.||||||||.|||||||||||||||||||||.: |....||: ||
Mosquito    66 KPTPFPYPPPQATEPTKTLKSLVNIRKESVRFVKVL-DAGGNGVV-KP----------------- 111

  Fly   131 VTIEDVDGNVLCSMGLGGGDADMTPPPPPCS------------YNIEFTFDSDAKCAITIYYFCS 183
                            .|||....|.|...:            |||||.||:|:.|.|||||||.
Mosquito   112 ----------------AGGDQVAKPNPATTTTTTTTNGTISNGYNIEFIFDADSPCHITIYYFCI 160

  Fly   184 EDVSPSGVTLVPRE-GLTSETYHYEKGINQCFSQPSHVFNPQQMPEDELGYSPGREQYPVAIHCV 247
            ||:.|.|...:.|: .:||||:|:::|:||.||.|.|:..|....|:.|.|||.::.:||.||||
Mosquito   161 EDIGPGGSNYISRDSSMTSETFHFQRGVNQLFSAPHHIIYPALYAEENLSYSPDKDTFPVVIHCV 225

  Fly   248 VEE------------------------------------GSDE------CRQSHTTICVIDHHPE 270
            |.|                                    |.|.      .||||.|||||||| .
Mosquito   226 VGEAATGGGNSAVANSNTTTVTTITNNNSALTAGVASDGGGDSGGAGPGSRQSHATICVIDHH-S 289

  Fly   271 NGSYVLRALKQKIFVDGLCYLLQEIYGIENKAVNKTSLDEEIDDHGSECVICMSETRDTLILPCR 335
            :|:|.|||||||||||||.||||||||||||..|||..|||.:|:||||||||.:||||||||||
Mosquito   290 DGTYALRALKQKIFVDGLYYLLQEIYGIENKLANKTVTDEETEDNGSECVICMCDTRDTLILPCR 354

  Fly   336 HLCLCNSCADSLRYQANNCPICRAPFRALLQIRAVQK-----------GISTHVLHQNTPTSAAG 389
            |||||||||||||||||||||||||||||||||||||           |.||... ||:..||.
Mosquito   355 HLCLCNSCADSLRYQANNCPICRAPFRALLQIRAVQKEGAGGGGGLPCGGSTPAA-QNSADSAD- 417

  Fly   390 EPAPVDVPPGYIPVSLIEALNGPPQYVARARNSEHDVTDSAATVAASTMTSADIKATSPIKSSSQ 454
                 ::|.||..:|||||||||              |.|...:..||.::|..:..|....|::
Mosquito   418 -----NIPAGYKTISLIEALNGP--------------TLSMKAINGSTDSTAGTENGSENNRSTE 463

  Fly   455 R----RPKIKKNASTCTSTSEV--GTITNQSGGGN-----------------GSSTHSVEIESDP 496
            .    |.|:.|:::..:|..|:  |:|.::....:                 ||...:|...::|
Mosquito   464 NGFGFRNKMTKSSTDHSSNGELANGSIVSEKSSSDIRMHLLASDETNAIAEAGSGGTNVGGIANP 528

  Fly   497 KKSSTATCTSPTLGASTSPEPKQDKLQIVNERKYPRS------TAGSGGDGSAG----------- 544
                |..||...|.:..||..::..   |::.|.||.      ...||.:||.|
Mosquito   529 ----TTVCTKKELLSKHSPLMQRAP---VSKDKNPREKGSLHRIGNSGTNGSNGGALVSSKSKSP 586

  Fly   545 ---------------------------------TDDDVDSENEKLSPLL------SPGSKSKNVS 570
                                             |::|.|||.|||||||      ..|||..:::
Mosquito   587 SDRTIGFHLVHEKPAAPGAALVGKMPDSKLTDLTENDDDSEAEKLSPLLRKSDSYDAGSKLGDMA 651

  Fly   571 SKSLKQVVACLEADDDVDNKSSTGDGPTEESS-------LKKGSSIKRTKPRPE----------- 617
            .|.|.           :....:.|:...|::|       |.||:.|.......|
Mosquito   652 MKKLL-----------IGGSGTIGEPVKEKTSPSAVIKELLKGAIIGSDDIGVEGGAVEMGLVGG 705

  Fly   618 LSGSGAPSPAEATAEDSDYYTPEDTQNSILSPLCPTERAKSGDPLGAGSLGNGGLSVGRSAGSVG 682
            ..|:|....:..|.:..|:|||||...:  |||    ::...|......|..  :..||.
Mosquito   706 NRGAGGAIISIVTDDSEDFYTPEDPPAT--SPL----KSIDDDDDELPKLAE--IDTGRK----- 757

  Fly   683 GQAGVGPVVVGFSSAVKKNLHKKSTSVGNMVGSGSVTTVVDLKSN-NVSSLPDMLDSPISGNS-A 745
                   ::|..::         :|:.|..:||.....:..||.. :..|||   |||||||| .
Mosquito   758 -------MLVAAAA---------TTAPGANLGSAPPAALSVLKEEFSQGSLP---DSPISGNSQT 803

  Fly   746 STRSSSDSYSSSSSTKQLLSSN--PTTTAANIIVD-DKTA 782
            |||||||||||||||:|||||.  |..|..:::.. |.||
Mosquito   804 STRSSSDSYSSSSSTRQLLSSGAVPNDTPTHVLSSCDSTA 843

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mrgn1	NP_572915.1	PEX10	<255..359	CDD:227861	86/103 (83%)
		RING_Ubox	314..372	CDD:473075	54/57 (95%)
Mrgn1	XP_061508803.1	None