Protein Alignment CG9941 and RNF157

DIOPT Version :9

• Sequence 1: NP_572915.1
• Gene: CG9941 / 32330
• FlyBaseID: FBgn0030514
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: XP_016879606.1
• Gene: RNF157 / 114804
• HGNCID: 29402
• Length: 688
• Species: Homo sapiens
• Alignment Length: 693
• Identity: 254/693 - (36%)
• Similarity: 353/693 - (50%)
• Gaps: 148/693 - (21%)

  Fly     1 MGNFVSRQNAAVEEADPSTNNAYKYPPRMGNFFGTHFIMGGERFDTPQPESYLFGENADLNFLGN 65
            ||...|||:|.|||.|..:|:.|:|||:.|::|.:|||||||:||:..||.||||||:|||||||
Human     1 MGALTSRQHAGVEEVDIPSNSVYRYPPKSGSYFASHFIMGGEKFDSTHPEGYLFGENSDLNFLGN 65

  Fly    66 RPTAFPY--PPPQANEPTKTLKSLVNIRKESVRFVKTMNDKKLGGVLEKPKMKEIDRDLDLDKEK 128
            ||..|||  ||||  ||.|||:|||||||:::|.||...:.|..|                 :|.
Human    66 RPVVFPYAAPPPQ--EPVKTLRSLVNIRKDTLRLVKCAEEVKSPG-----------------EEA 111

  Fly   129 SNVTIEDVDGNVLCSMGLGGGDADMTPPPPPCSYNIEFTFDSDAKCAITIYYFCSEDVSPSGVTL 193
            |...:.                           ||:|||||:||:.||||||..:|:......:.
Human   112 SKAKVH---------------------------YNVEFTFDTDARVAITIYYQATEEFQNGIASY 149

  Fly   194 VPRE-GLTSETYHYEKGINQCFSQPSHVFNPQQMPEDELGYSPGREQYPVAIHCVVEEGSDECRQ 257
            :|:: .|.|||..|::|:.|.|..|||..:|.:..|:|||:...||.||:.:|.||:||.:....
Human   150 IPKDNSLQSETVQYKRGVCQQFCLPSHTVDPSEWAEEELGFDLDREVYPLVVHAVVDEGDEYFGH 214

  Fly   258 SHTTICVIDHHPENGSYVLRALKQKIFVDGLCYLLQEIYGIENKAVNKTS--LDEEIDDHGSECV 320
            .|..:...:.|.: |::.::.||||..|||:.||||||||||||...:.|  .::|:.|:.:|||
Human   215 CHVLLGTFEKHTD-GTFCVKPLKQKQVVDGVSYLLQEIYGIENKYNTQDSKVAEDEVSDNSAECV 278

  Fly   321 ICMSETRDTLILPCRHLCLCNSCADSLRYQANNCPICRAPFRALLQIRAVQKGI------STHVL 379
            :|:|:.|||||||||||||||:|||:||||||||||||.||||||||||::|.:      |.:.:
Human   279 VCLSDVRDTLILPCRHLCLCNTCADTLRYQANNCPICRLPFRALLQIRAMRKKLGPLSPTSFNPI 343

  Fly   380 HQNTPTSAAGEPAPVDVPPGYIPVSLIEALNGPPQYVARARNSEHDVTDSAATVAASTMTSADIK 444
            ..:..:.:...|:..::||||..|||:||||||             :|.|.|......:....:.
Human   344 ISSQTSDSEEHPSSENIPPGYEVVSLLEALNGP-------------LTPSPAVPPLHVLGDGHLS 395

  Fly   445 ATSP-------------------IKSSSQRRPKIKKNASTCTSTSEVGTITNQSGGGNGSSTHSV 490
            ...|                   :..||.:..|:||:.|..||.             |.|..|..
Human   396 GMLPSYGSDGHLPPVRTISPLDRLSDSSSQGLKLKKSLSKSTSQ-------------NSSVLHEE 447

  Fly   491 EIESDPKKSSTATCTSPT---LGASTSPEPKQDKLQIVNERKYPRSTAGSGGDGSAGTDDDVDSE 552
            |.|....:|.|.....|:   ||......|:.:.|.:        |::|:           :|..
Human   448 EDEHSCSESETQLSQRPSVQHLGEECGVTPESENLTL--------SSSGA-----------IDQS 493

  Fly   553 NEKLSPLLSPGSKSKNVSSKSLKQVVACLEAD----DDVDNKSSTGDGP-TEESSLKKGSSIKRT 612
            :...:||.|..|..:..:|.||.|.|..:.:.    |.|.:.|.:...| |||    :|.::...
Human   494 SCTGTPLSSTISSPEGPASSSLAQSVMSMASSQISTDTVSSMSGSYIAPGTEE----EGEALSSP 554

  Fly   613 KP---RPELSGSGAPS----------PA-EATAEDSDYYTPED 641
            :|   .|...|.|.|:          || |..||.:|....||
Human   555 QPASRAPSEEGEGLPAESPDSNFAGLPAGEQDAEGNDVIEEED 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9941	NP_572915.1	zf-C3HC4_3	318..360	CDD:290631	35/41 (85%)
RNF157	XP_016879606.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145988
Domainoid	1	1.000	249	1.000	Domainoid score	I2129
eggNOG	1	0.900	-	-		E1_KOG4265
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	389	1.000	Inparanoid score	I2016
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D172099at33208
OrthoFinder	1	1.000	-	-		FOG0001616
OrthoInspector	1	1.000	-	-		otm41176
orthoMCL	1	0.900	-	-		OOG6_102038
Panther	1	1.100	-	-	LDO	PTHR22996
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5735
SonicParanoid	1	1.000	-	-		X1025
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.790