Protein Alignment HOXD4 and Abd-B

DIOPT Version :10

• Sequence 1: NP_055436.2
• Gene: HOXD4 / 3233
• HGNCID: 5138
• Length: 255
• Species: Homo sapiens
• Sequence 2: NP_524896.2
• Gene: Abd-B / 47763
• FlyBaseID: FBgn0000015
• Length: 493
• Species: Drosophila melanogaster
• Alignment Length: 246
• Identity: 64/246 - (26%)
• Similarity: 100/246 - (40%)
• Gaps: 59/246 - (23%)

Human    11 KYVDPKFPP---CEEYLQGGYLGEQGADYYGGGAQGADFQPPGLYPRPDFGEQPFGGSGPGPGSA 72
            :|..|.:.|   ........|:.|..........|..:......|..|.:       |.||....
  Fly   292 QYWGPNYRPDQTTSAAAAAAYMNEAERHVSAAARQSVEGTSTSSYEPPTY-------SSPGGLRG 349

Human    73 LPARGHGQEPGGPGGHYAAPGEPCPAPPAPPPAPLPGARAYSQSDPKQPPSGTALKQPAVVYPWM 137
            .|:..:... |..||.......||        .|.||                       ::.|.
  Fly   350 YPSENYSSS-GASGGLSVGAVGPC--------TPNPG-----------------------LHEWT 382

Human   138 KKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWF 202
            .:|.|            ::.|..|::.|.|||||||.||.|:::::|.|:|..|.|:|||:||||
  Fly   383 GQVSV------------RKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVKIWF 435

Human   203 QNRRMKWKKDHKLPNTKGRSSSSSSSSSCSSSVAPSQHLQPMAKDHHTDLT 253
            ||||||.||     |::.:::..:::::.||:...:|..|.....||.:|:
  Fly   436 QNRRMKNKK-----NSQRQANQQNNNNNSSSNHNHAQATQQHHSGHHLNLS 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXD4	NP_055436.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..127		16/95 (17%)
		Antp-type hexapeptide	133..138		1/4 (25%)
		Homeodomain	155..211	CDD:459649	31/55 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..255		8/42 (19%)
Abd-B	NP_524896.2	Homeodomain	388..444	CDD:459649	31/55 (56%)