Protein Alignment HOXD4 and ro

DIOPT Version :10

• Sequence 1: NP_055436.2
• Gene: HOXD4 / 3233
• HGNCID: 5138
• Length: 255
• Species: Homo sapiens
• Sequence 2: NP_524521.1
• Gene: ro / 43234
• FlyBaseID: FBgn0003267
• Length: 350
• Species: Drosophila melanogaster
• Alignment Length: 234
• Identity: 65/234 - (27%)
• Similarity: 87/234 - (37%)
• Gaps: 87/234 - (37%)

Human    16 KFPPCEEYLQGGYLGEQGADYY--GGGAQGADFQ------PPGLYPRPDFGEQPFGGSGPGPGSA 72
            |.|||:            ..|:  ||.....|..      ....||..||
  Fly    70 KPPPCD------------TPYHSDGGSVSSPDISISDERTSLAAYPAYDF--------------- 107

Human    73 LPARGHGQE-PGGPGGHYAAPGEPCPAPP----------APPPAPLPGARAYSQSDPKQP---PS 123
               .||.:: |..|...:.........||          :||||...|..|    :|..|   |:
  Fly   108 ---YGHAKDYPQHPSQQHQQHHHHHHHPPQLVHQKLSYVSPPPAIAAGGAA----NPVLPHAFPA 165

Human   124 GTALKQPAVVYPWMKKVHVNSVNPNYTG-------------GEPKRSRTAYTRQQVLELEKEFHF 175
            |         :|         .:|:::.             |..:|.||.::.:|.|.||.|||.
  Fly   166 G---------FP---------SDPHFSAGFSAFLARRRRKEGRQRRQRTTFSTEQTLRLEVEFHR 212

Human   176 NRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHK 214
            |.|::|.||.|:|.||.|:|.||||||||||.|.|:..|
  Fly   213 NEYISRSRRFELAETLRLTETQIKIWFQNRRAKDKRIEK 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXD4	NP_055436.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..127		24/117 (21%)
		Antp-type hexapeptide	133..138		1/4 (25%)
		Homeodomain	155..211	CDD:459649	32/55 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..255		1/3 (33%)
ro	NP_524521.1	Homeodomain	196..248	CDD:459649	30/51 (59%)