Protein Alignment HOXD4 and CG18599

DIOPT Version :10

• Sequence 1: NP_055436.2
• Gene: HOXD4 / 3233
• HGNCID: 5138
• Length: 255
• Species: Homo sapiens
• Sequence 2: NP_650701.1
• Gene: CG18599 / 42191
• FlyBaseID: FBgn0038592
• Length: 475
• Species: Drosophila melanogaster
• Alignment Length: 201
• Identity: 58/201 - (28%)
• Similarity: 87/201 - (43%)
• Gaps: 38/201 - (18%)

Human    63 GGSGPGPGSALPA---------RGHGQEPGG----PGGHYAAPGEPCPAPPAPPPAPLPGARAYS 114
            |||..|..::.|:         .|:|:...|    |..|.|.......|..|.|.| |...:...
  Fly   223 GGSNSGNNNSSPSVNNFNCDSVAGNGRYLHGGHQHPHPHQAGFAAVAAAVGAAPSA-LQSLQQLH 286

Human   115 QSDPKQPPSGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYL 179
            |....|..:..:.::..:    ....|..|...|      ||.||.:|.:|:..||.||...:|:
  Fly   287 QQHHAQQQATLSFQREKL----KSDSHKKSALKN------KRVRTIFTPEQLECLEAEFERQQYM 341

Human   180 TRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDH--------------KLPNTKGRSSSSSSSSS 230
            ....|:.:||||.|:|.|:|:||||||:||:|.|              :||.|....:..|.|::
  Fly   342 VGPERLYLAHTLKLTEAQVKVWFQNRRIKWRKHHLELTQQRLALIRQTQLPGTSLLGNQVSVSAN 406

Human   231 CSSSVA 236
            .:.||:
  Fly   407 AAHSVS 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXD4	NP_055436.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..127		18/76 (24%)
		Antp-type hexapeptide	133..138		0/4 (0%)
		Homeodomain	155..211	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..255		8/39 (21%)
CG18599	NP_650701.1	Homeodomain	317..373	CDD:459649	28/55 (51%)