DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HOXD4 and ftz

DIOPT Version :9

Sequence 1:	NP_055436.2	Gene:	HOXD4 / 3233	HGNCID:	5138	Length:	255	Species:	Homo sapiens
Sequence 2:	NP_477498.1	Gene:	ftz / 40834	FlyBaseID:	FBgn0001077	Length:	410	Species:	Drosophila melanogaster

Alignment Length:	194	Identity:	76/194 - (39%)
Similarity:	96/194 - (49%)	Gaps:	53/194 - (27%)

- Green bases have known domain annotations that are detailed below.

Human    87 GHYAAPGEPCPAPPAPPPA--PLPGARAYSQSDPKQPP---SGTALKQPAVVYPWMKKVHVNS-- 144
            |.:|.|      ||..|.:  ||.|.     |.|.|.|   |.:|:.|           .:|.
  Fly   186 GDFATP------PPTTPTSLPPLEGI-----STPPQSPGEKSSSAVSQ-----------EINHRI 228

Human   145 -VNPNYTGG---------------EPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCL 193
             ..||..|.               :.||:|..|||.|.||||||||||||:||||||:||:.|.|
  Fly   229 VTAPNGAGDFNWSHIEETLASDCKDSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSL 293

Human   194 SERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSS-------SSSCSSSVAPSQHLQPMAKDHHT 250
            |||||||||||||||.|||..|.::.....:..:       ::|.:::.|||..: ||...|.|
  Fly   294 SERQIKIWFQNRRMKSKKDRTLDSSPEHCGAGYTAMLPPLEATSTATTGAPSVPV-PMYHHHQT 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HOXD4	NP_055436.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	31..127		14/44 (32%)
		Antp-type hexapeptide	133..138		0/4 (0%)
		Homeobox	157..210	CDD:306543	42/52 (81%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	212..255		10/46 (22%)
ftz	NP_477498.1	FTZ	1..248	CDD:281812	20/83 (24%)
ftz	NP_477498.1	Homeobox	257..310	CDD:278475	42/52 (81%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810