Protein Alignment HOXD4 and ftz

DIOPT Version :10

• Sequence 1: NP_055436.2
• Gene: HOXD4 / 3233
• HGNCID: 5138
• Length: 255
• Species: Homo sapiens
• Sequence 2: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Alignment Length: 194
• Identity: 76/194 - (39%)
• Similarity: 96/194 - (49%)
• Gaps: 53/194 - (27%)

Human    87 GHYAAPGEPCPAPPAPPPA--PLPGARAYSQSDPKQPP---SGTALKQPAVVYPWMKKVHVNS-- 144
            |.:|.|      ||..|.:  ||.|.     |.|.|.|   |.:|:.|           .:|.
  Fly   186 GDFATP------PPTTPTSLPPLEGI-----STPPQSPGEKSSSAVSQ-----------EINHRI 228

Human   145 -VNPNYTGG---------------EPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCL 193
             ..||..|.               :.||:|..|||.|.||||||||||||:||||||:||:.|.|
  Fly   229 VTAPNGAGDFNWSHIEETLASDCKDSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSL 293

Human   194 SERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSS-------SSSCSSSVAPSQHLQPMAKDHHT 250
            |||||||||||||||.|||..|.::.....:..:       ::|.:::.|||..: ||...|.|
  Fly   294 SERQIKIWFQNRRMKSKKDRTLDSSPEHCGAGYTAMLPPLEATSTATTGAPSVPV-PMYHHHQT 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXD4	NP_055436.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..127		14/44 (32%)
		Antp-type hexapeptide	133..138		0/4 (0%)
		Homeodomain	155..211	CDD:459649	44/55 (80%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..255		10/46 (22%)
ftz	NP_477498.1	FTZ	1..248	CDD:397787	20/83 (24%)
		Homeodomain	255..311	CDD:459649	44/55 (80%)
		KLF1_2_4_N	<321..404	CDD:425360	8/37 (22%)